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Abilify used for the treatment of acute episodes of schizophrenia (including as maintenance funds). Buy Abilify only after consulting with your doctor.
Abilify also used to treat acute manic episodes of bipolar disorder type I, including patients who have recently given mixed or manic episode (maintenance).
Contra Abilify
Abilify is contraindicated in patients under 18 years of age and patients with hypersensitivity to any component of the drug.
Side effects Abilify
Abilify can cause the certain side effects (check with your doctor)
International name:
Aripiprazole
Group Affiliation:
Antipsychotic (neuroleptic)
Description of the active substance (INN):
Aripiprazole
Description of the product brand name:
Abilify
Dosage form:
Tablets
Pharmacological Effects:
Neuroleptic. Presumably the therapeutic effect of aripiprazole in schizophrenia is caused by a combination of partial agonist activity on D2 dopamine and serotonin receptors 5NT1a and antagonistic activity against 5NT2 serotonin receptor. Aripiprazole has a high affinity in vitro to the D2 and D3 dopamine receptors, and 5NT1a 5NT2a serotonin receptors and moderate affinity for dopamine D4, 5NT2s 5NT7 and serotonin, alpha 1-adrenoreceptors and H1 histamine receptors. Aripiprazole is also characterized by a moderate affinity for serotonin reuptake sites and the lack of affinity for muscarinic receptors. Aripiprazole in animal experiments showed antagonism against dopaminergic hyperactivity and dopaminergic agonism against gipoaktivnosti. Interaction not only with dopamine and serotonin receptors explains some of the clinical effects of aripiprazole.
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Indications:
An acute attack of schizophrenia, as well as for maintenance therapy. Acute manic episodes of bipolar disorder type I and for maintenance therapy in patients with bipolar disorder type I, has recently suffered a manic or mixed episode.
Contraindications:
Hypersensitivity, the age of 18 years, during lactation.
Dosage and administration:
Inside, regardless of the meal, a once a day. Schizophrenia: initial dose 10-15 mg / day maintenance dose - 15 mg / day in clinical trials, the effectiveness of the drug in doses ranging from 10 to 30 mg / day. Manic episodes in bipolar disorder: initial dose 15-30 mg / day. If necessary, dose adjustment is carried out at intervals of not less than 24 h. In clinical studies demonstrated efficacy at doses of 15-30 mg / day with a manic episode at the reception for 3-12 weeks. Safety of doses above 30 mg / day in clinical trials has not been evaluated. Dose adjustment in patients older than 65 years, as well as in chronic renal failure and hepatic failure (class A, B and C on the classification of Child-Pyuga) is not required.
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Cymbalta (Duloxetine)
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Fenofibrate - Finasteride - Fioricet - Fiorinal - Fiorinal with Codeine
August 13, 2009 | Leave a Comment
Generic Name
Fenofibrate (fen-oe-Flli-brace) IM
Brand Names
Antara TriCor
Lipoten Triglide Lofibra
Type of Drug
Anti-hyperlipidemic (blood-fat reducer).
Prescribed For
High blood cholesterol and/or triglycerides; also prescribed for syndrome X, a condition which increases the risk of type 2 diabetes.
General Information
Fenofibrate works by interfering with the body’s ability to make triglyceride and by increasing its breakdown by enzymes in the body. It also reduces levels of uric acid, total cholesterol, low-density lipoprotein (LDL) cholesterol—the “bad” cholesterol—and other blood lipids. High-density lipoprotein (HDL) cholesterol—the “good” cholesterol—levels are increased. This drug should only be used in people with very high triglyceride levels who are at risk for pancreatitis (inflammation of the pancreas) and have not responded to other treatments, including statin drugs. Generic fenofibrate is not equivalent to the TriCor brand because of a new product formulation and should not be substituted for the brand unless your doctor approves of the switch.
Cautions and Warnings
Do not take fenofibrate if you are allergic or sensitive to any of its ingredients.
People taking fenofibrate and other triglyceride-lowering drugs are mate WOV to die from causes unrelated to triglyceride levels. Fenofibrate reduces the risk of a heart attack or other cardiac event in people with high triglyceride levels and low levels of HDL cholesterol, especially among people with diabetes. The evidence for this benefit is not as strong as it is for the statin drugs.
People taking fenofibrate and gemfibrozil may develop pancreatitis (inflammation of the pancreas).
People with liver or severe kidney disease should avoid fenofibrate. People with less severe kidney disease require reduced
dosage.
People taking fenofibrate are more likely to develop gallstones.
Fenofibrate can destroy muscle cells, leading to kidney failure, especially when combined with a statin cholesterol-lowering drug see “Drug Interactions”).
Possible Side Effects
• Most common: abnormal liver function, abdominal pain, and respiratory disorders.
♦ Common: rash, headache, upset stomach, pain, weakness, tiredness, and flu-like symptoms.
♦ Less common: joint pain, abnormal heart rhythms, reduced sex drive, dizziness, increased appetite, sleeplessness, tingling in the hands or feet, nausea, vomiting, diarrhea, abdominal pain, constipation, stomach noise or gas, frequent urination, vaginal irritation, runny nose, cough, sinus irritation, eye irritation, blurred vision, conjunctivitis (pinkeye). earache, and tiny particles inside the eye (”floaters”).
♦ Rare: allergic reactions including severe rash, itching, liver inflammation or enlargement, gallstones, gallbladder disease, muscle aches, and increased sensitivity to the sun. Contact your doctor if you experience any side effect not listed above.
Drug Interactions
• Combining fenofibrate and a statin cholesterol-lowering drug (atorvastatin, cerivastatin, fluvastatin, lovastatin, pravastatin, or simvastatin) can lead to severe muscle pain, muscle cell destruction, and kidney failure. If you have extremely high blood-fat levels, the potential benefits of this combination may outweigh the risks. In people taking this combination, the health of muscles and kidneys must be monitored regularly via blood tests.
• Fenofibrate increases the effects of anticoagulant (blood-thinning) drugs. Your anticoagulant dosage may need an adjustment.
• Combining fenofibrate and cyclosporine can increase the risk of kidney toxicity. This combination should only be used if it is absolutely necessary and the lowest possible dosage is
taken.
• If you are taking cholestyramine or colestipol (both are used
to reduce blood-fat levels) as well as fenofibrate, take the
fenofibrate at least 1 hour before or 4-6 hours after these
drugs.
Food Interactions
All forms of fenofibrate, except TriCor, should be taken with food to get the best effect. TriCor may be taken without regard to food or meals.
Usual Dose
These products may not be substituted for each other because of important dosage differences.
Antara
Adult: 43-130 mg a day with food.
Senior: Begin with 43 mg a day. This dosage also applies to people with kidney disease.
Child: not recommended.
Lofibra
Adult: 67-200 mg a day with food.
Senior: Begin with 67 mg a day. This beginning dosage also applies to people with kidney disease.
Child: not recommended.
Lipofen
Adult: 50-150 mg a day with food.
Senior: Begin with 50 mg a day. This dosage also applies to people with kidney disease.
Child: not recommended.
TriCor
Adult: 48-145 mg a day.
Senior: Begin with 48 mg a day. This dosage also applies to
people with kidney disease. Child; mk recommended.
Triglide
Adult: 50-160 mg a day.
Senior: Begin with 50 mg a day. This dosage also applies to
people with kidney disease. Child: not recommended.
Overdosage
Little is known about the effects of fenofibrate overdose. Victims should be taken to a hospital emergency room. ALWAYS bring the prescription bottle or container.
Special Information
People should take fenofibrate only after a triglyceride- lowering diet and other medications have failed. While taking fenofibrate, follow the diet recommended by your doctor.
If you forget a dose, take it as soon as you remember. If it is almost time for your next dose, skip the forgotten dose and continue with your regular schedule.
Special Populations
Pregnancy/Breast-feeding: Fenofibrate causes fetal injury and death in animal studies. When this drug is considered crucial by your doctor, its potential benefits must be carefully weighed against its risks.
This drug should not be taken by nursing mothers because of its potential to affect the nursing infant.
Seniors: Seniors are more likely to experience side effects and should never start with more than the lowest recommended dosage.
Generic Name
Finasteride (fin-ASS-ter-ide) 19
Brand Names
Proscar Propecia
The information in this profile also applies to the following drug:
Generic Ingredient: Dutasteride Avodart
Type of Drug
Alpha-reductase inhibitor and androgen hormone inhibitor.
Prescribed for
Benign prostatic hyperplasia (BPH) and male-pattern baldness. May also play a role in preventing prostrate cancer.
General Information
Finasteride works by interfering with the action of the enzyme alphareductase, which converts testosterone into 5-dihydrotestosterone (DHT). By suppressing DHT levels, finasteride reduces the size of the prostate in most men who take the drug for BPH. You may need to take finasteride for 6-12 months before its effects can be
assessed.
Urine flow improves in about 60% of men taking finasteride for BPH and symptoms improve in about 30%. In one study, men experienced a significant regression in prostate size after 3 months, and the reduction was maintained through the 12-month study period: these men experienced a significant improvement in urine flow that could be maintained up to 36 months.
Studies of finasteride for hair loss on the top and back-middle of the scalp show new hair growth in 65-80% of men taking the drug continuously for 2 years. The drug must be taken for 3 months or more before it begins to have an effect and must be taken continuously to maintain hair growth. Once you stop taking this drug, any new hair you have grown is likely to fall out in the next 12 months. Between 14-17% of men taking the drug continued to lose hair throughout the study period.
Finasteride has been studied as therapy following radical prostatectomy surgery and in the prevention of first-stage prostate cancer, acne in women, and unusual hairiness.
Cautions and Warnings
Do not take finasteride if you are allergic or sensitive to any of its ingredients.
This drug should not be used in women or children. Pregnant women must not handle the tablets and capsules because of the risk to the fetus.
People who do not respond to finasteride may have a condition that causes BPH-like symptoms, such as prostate cancer, bladder or nerve disorders, or physical obstruction of the urinary tubes. Finasteride cannot be used to treat these conditions.
Because it is broken down in the liver, finasteride must be used with caution by people with liver disease.
Finasteride may mask symptoms of prostate cancer by causing a reduction in the level of prostate-specific antigen (PSA), an increasingly acknowledged indicator of prostate cancer.
Possible Side Effects
Side effects are generally mild and often subside with continued use of the drug.
Drug Interactions
• Finasteride may reduce the effectiveness of theophylline and aminophylline, although dosage adjustments usually are not required.
• Finasteride affects the PSA blood test used for prostate cancer screening. Be sure your doctor knows you are taking this drug if you have a PSA test done or are being tested for prostate cancer.
• Dustasteride blood levels may increase when mixed with ritonavir, ketoconazole, cimetidine, and ciprofloxacin, all of which are inhibitors of a liver enzyme called CYP3A4. Blood levels of dutasteride also increase with verapamil and diltiazem.
Food Interactions
You may take finasteride with food if it upsets your stomach.
Usual Dose
Outasteride
Adult: 0.5 mg (1 capsule) once a day. Child: not recommended.
Finasteride
Adult: BPH-5 mg once a day. Male-pattern baldness-1 mg once a day.
Child: not recommended.
Women should not take finasteride. Overdosage
S%’& Ptecls are unlikely. Doses of dutasteride as high as 400 mg a day have been taken with no adverse side effects. Call your local poison control center or a hospital emergency room for more information. If you seek treatment, ALWAYS bring the prescription bottle or container.
Possible Side Effects (continued)
v Common: impotence, loss of sex semen, breast tenderness an
• and drug sensitivity reaction
• rash.
x drive, decreased amount nd enlargement, testicular ions including lip swelling Special Information
Women who are or might be pregnant should not handle crushed finasteride tablets because small amounts of the drug may be absorbed into the blood, possibly affecting the fetus.
If your sexual partner is or might be pregnant and you start taking finasteride, you must wear a condom during sex to avoid directly exposing her to finasteride in the semen.
Semen volume may decrease while on finasteride. Impotence or reduced sex drive is also a risk.
If you forget a dose, take it as soon as you remember. If it is almost time for your next dose, skip the one you forgot and continue with your regular schedule. Do not take a double dose. Call your doctor if you miss a dose for 2 or more days.
Special Populations
Pregnancy/Breast-feeding: This drug is not intended for women. Finasteride will harm the fetus if taken during pregnancy. It is not known if finasteride passes into breast milk.
Seniors: Seniors with liver disease should use this drug with caution.
Brand Name
Fioricet
Generic Ingredients
Acetaminophen + Butalbital + Caffeine 91
Other Brand Names
Americet Femcet
Dolgic LQ Margesic
Dolgic Plus Medigesic
Esgic Repan
Esgic-Plus Triad
Type 101 Drug
Barbiturate and analgesic (pain reliever) combination.
Prescribed For
Symptom relief of tension headache.
General Information
Fioricet is one of many combination products containing a barbiturate—butalbital—and an analgesic—acetaminophen. Products of this kind also often contain a sedative or a narcotic. Other analgesic combinations, such as Rorinal, substitute aspirin for
acetaminophen.
Cautions and Warnings
Do not take Fioricet if you are allergic or sensitive to any of its ingredients.
Use this drug with caution if you have kidney or liver disease or a history of porphyria.
Chronic (long-term) use of Fioricet may lead to drug dependence or addiction. It is not recommended for multiple or recurrent headaches.
Butalbital is a respiratory depressant and affects the central nervous system (CNS), producing drowsiness, tiredness, and an inability to concentrate. Alcohol increases the CNS depression caused by this drug.
The safety and effectiveness of these medications have not been established in children under age 12.
For additional information see “Cautions and Warnings” in Acetaminophen (page 7).
Possible Side Effects
♦ Most common: lightheadedness, dizziness, sedation, shortness of breath, nausea, vomiting, upset stomach and a feeling of intoxication.
V Less common: weakness, headache, agitation, tremor, uncoordinated muscle movement, disorientation, dry mouth, constipation, facial flushing, changes in heart rate, palpitations, feeling faint, urinary difficulties, rash, and itching.
For additional information see “Possible Side Effects” in Acet-
aminophen (page 7).
Drug Interactions
• Combining Fioricet with alcohol, sedatives, barbiturates, sleeping pills, antihistamines, monoamine oxidase inhibitor antidepressants, or other CNS depressants may cause tiredness, drowsiness, and trouble concentrating.
These medications may reduce the effectiveness of corticosteroids, contraceptives containing estrogen, beta blockers (e.g. propranolol), doxycycline, felodipine, griseofulvin, nifedipine, phenylbutazone, quinine, theophylline, warfarin, and tricyclic antidepressants.
For additional information see “Drug Interactions” in Acetaminophen (page 7).
Food Interactions
Fioricet is best taken on an empty stomach but may be taken with food if it upsets your stomach.
Usual Dose
1-2 tablets or capsules every 4 hours or as needed; do not exceed 6 doses a day.
Overdosage
Symptoms include breathing difficulties, nervousness progressing to stupor or coma, pinpointed pupils, cold and clammy skin and lowered heart rate or blood pressure, nausea, vomiting, dizziness, ringing in the ears, facial flushing, sweating, and thirst. Take the victim to a hospital emergency room immediately. ALWAYS bring the prescription bottle or container.
Special Information
Fioricet may cause drowsiness. Be careful when driving or performing any task that requires concentration.
You should avoid alcohol while taking this medication.
Do not take Fioricet for longer or in amounts greater than prescribed.
If you have been taking this medication for more than a few weeks, do not stop taking it without your doctor’s instruction. Suddenly stopping Fioricet may lead to withdrawal symptoms.
Call your doctor if your headache or pain persists or gets worse, or if you develop side effects that are bothersome or persistent.
If you forget a dose, take it as soon as you remember. If it is almost time for your next dose, skip the one and continue
W<tkh IV61 schedule. Do not take a double dose.
For additional information see “Special Information” in Acetaminophen (page 7).
Special Populations
Pregnancy/Breast-feeding: Fioricet should not be taken during pregnancy. It is associated with birth defects, prolonged labor and delayed delivery, and breathing problems in newborns. Regular use of Fioricet during the last 3 months of pregnancy may also cause drug dependency in the newborn.
Fioricet passes into breast milk. Breast-feeding while using Fioricet may cause babies to become tired, short of breath, or have a slow heartbeat. Nursing mothers who must take this drug should use infant formula.
Seniors: Fioricet may have a greater depressant effect on seniors. Seniors are also more likely to experience stimulation and disorientation.
Brand Name
Fiorinal
Generic Ingredients
Aspirin + Butalbital + Caffeine &9
Other Brand Names
Butalgen Fiorimor
Farbital Fortabs
Fiorigen Lanorinal
Type of Drug
Barbiturate and analgesic (pain reliever) combination. Prescribed For
Symptom relief of tension headache.
General Information
Pain relief products often combine an analgesic with a sedative. The analgesic ingredient in Fiorinal is aspirin; other brand-name products, such as Esgic and Fioricet, contain acetaminophen. The sedative ingredient in pain-relief combinations may be a barbiturate, narcotic, or other sedative. Fiorinal contains the barbiturate butalbital. Fiorinal also contains caffeine, which is ofte” \Ased in analgesic combinations that km,-M beadache because it enhances kkNt %m-relieving effect of aspirin.
Cautions and Warnings
Do not take Fiorinal if you are allergic or sensitive to any of its ingredients.
Do not give Fiorinal to children or teenagers with chickenpox or flu-like symptoms due to the aspirin content and danger of
Reye’s syndrome.
Use Fiorinal with extreme caution if you suffer from peptic ulcer,
problems with blood clotting or other bleeding disorders, or are
about to have surgery.
This drug should be used with caution if you have kidney or
liver disease, diabetes, or a history of porphyria.
Long-term use of this drug may cause drug dependence and addiction. It is not recommended for the treatment of multiple recurrent headaches.
Butalbital is a respiratory depressant and affects the central nervous system (CNS), producing drowsiness, tiredness, and an
inability to concentrate. Alcohol increases the CNS depression caused by butalbital.
The safety and efficacy of Fiorinal use in children under age 12 has not been established.
For additional information see “Cautions and Warnings” in Aspirin (page 110).
Possible Side Effects
✓ Most common: lightheadedness, dizziness, and sedation.
♦ Less common: nausea, vomiting, flatulence, and rash. For additional information see “Possible Side Effects” in Aspirin (page 110).
Drug Interactions
• Combining Fiorinal with alcohol, sedatives, barbiturates, sleeping pills, antihistamines, monoamine oxidase inhibitor antidepressants, or other CNS depressants may cause tiredness, drowsiness, and trouble concentrating.
• Fiorinal may enhance the effects of oral anticoagulants (blood thinners), oral antidiabetes drugs, insulin, and mmsteroidal anti-inflammatory drugs ~VASAYDs).
• F10final may decrease the effectiveness of medications taken for gout, including probenicid and sulfinpyrazone.
For additional information see “Drug Interactions” in Aspirin (page 110).
Food Interactions
Fiorinal is best taken on an empty stomach but may be taken with
food if it upsets your stomach.
usual Dose
1-2 tablets or capsules every 4 hours or as needed. Do not exceed
6 doses a day. Overdosage
Symptoms include breathing difficulties, nervousness progressing to stupor or coma, pinpointed pupils, cold and clammy skin, lowered heart rate or blood pressure, nausea, vomiting, stomach pain, dizziness, ringing in the ears, flushing, sweating, and thirst. Symptoms of mild overdose are rapid and deep breathing, nausea, vomiting, dizziness, ringing or buzzing in the ears, flushing, sweating, thirst, headache, drowsiness, diarrhea, and rapid heartbeat. Severe overdose may cause fever, excitement, confusion, convulsions, liver or kidney failure, coma, and bleeding. Take the victim to a hospital emergency room immediately. ALWAYS bring the prescription bottle or container.
Special Information
Fiorinal may cause drowsiness. Be careful when driving or performing any task that requires concentration.
Avoid alcohol while taking Fiorinal.
If you have been taking this medication for more than a few weeks, do not stop taking it without your doctor’s instruction. Suddenly stopping this drug may lead to withdrawal symptoms.
Do not take Fiorinal for longer or in amounts greater than prescribed.
Call your doctor if your headache pain persists or gets worse, or if you develop any bothersome or persistent side effect.
If you forget a dose, take it as soon as you remember. If it is almost time for your next dose, skip the dose you forgot and continue with your regular schedule. Do not take a double dose.
For additional information see “Special Information” in Aspirin (page 110).
Special Populations
PregriancylBreast-feeding. Fiorinal should not be taken during pregnancy. Pregnant women taking it may experience prolonged labor, delayed delivery, and bleeding problems. Fiorinal increases the risk of birth defects and may cause breathing or bleeding prob-lems in newborns. Regular use of Fiorinal during the last 3 months of pregnancy may also cause drug dependency in the newborn.
Fiorinal passes into breast milk. Breast-feeding while using Fiorinal may cause tiredness, shortness of breath, or slowed heartbeat in the baby. Nursing mothers who must take Fiorinal should use infant formula.
Seniors: Fiorinal may have a greater depressant effect on seniors. Seniors are also more likely to experience stimulation and disorientation.
Brand Name
Fiorinal with Codeine
Generic Ingredients
Aspirin + Butalbital + Caffeine + Codeine Phosphate 19
Type of Drug
Barbiturate, narcotic, and analgesic (pain reliever) combination.
Prescribed For
Symptom relief of tension headache.
General Information
Fiorinal with Codeine is one of many combination products containing a barbiturate, an analgesic, and a narcotic. In Fiorinal with Codeine, butalbital is the barbiturate, aspirin is the analgesic, and codeine is the narcotic. These products often also contain a sedative, and acetaminophen may be substituted for aspirin.
Cautions and Warnings
Do not take Fiorinal with Codeine if you are allergic or sensitive to any of its ingredients. Even recommended doses of aspirin can cause severe allergic reaction in those with an aspirin allergy.
Do not take this medication if you suffer from peptic ulcer, bleeding disorders, or a history of porphyria.
Use this medication with cautiOi) 11 you have kidney or liver
disease of diabetes.
Fiorinal with Codeine may cause postural low blood pressure (symptoms include dizziness or fainting when rising from a sitting or lying position).
Long-term use of this drug may cause drug dependence or addiction.
It is not recommended for treatment of multiple, recurrent head-
aches.
Fiorinal with Codeine is a respiratory depressant and affects the
central nervous system (CNS), producing sleepiness, tiredness, or inability to concentrate. Alcohol increases the depression caused
by codeine and butalbital.
Do not give Fiorinal with Codeine to children or teenagers with
chickenpox or flu-like symptoms. The aspirin content presents the
danger of Reye’s syndrome.
For additional information see “Cautions and Warnings” in As-
pirin (page 110).
Possible Side Effects
✓ Most common: dizziness, sleepiness, nausea, and vomiting.
♦ Less common: dry mouth, difficulty swallowing, heartburn, rapid heart rate, leg pain and muscle fatigue, urinary problems, rash, fever, earache, stuffy nose, and ringing in the ears. Narcotic analgesics may aggravate convulsions in those who have had them.
For additional information see “Possible Side Effects” in Aspirin (page 110).
Drug Interactions
• Interaction with alcohol, sedatives, barbiturates, sleeping pills, antihistamines, or other drugs that produce sedation may cause tiredness, drowsiness, and trouble concentrating.
• Taking Fiorinal with Codeine with a monoamine oxidase inhibitor antidepressant may cause increased central nervous system effects.
• This medication may reduce the effectiveness of medications for the treatment of gout including probenicid and sulfapyrazone.
• Fiorinal with Codeine may enhance the effects of blood thin- ners, oral antidiabetes drugs, insulin, and anti-inflammatory drugs (NSAIDs).
For additional information see “Drug Interactions” in Aspirin (page 110).
Food Interactions
Fiorinal with Codeine is best taken on an empty stomach but may be taken with food if it upsets your stomach.
Usual Dose
1-2 tablets or capsules every 4 hours or as needed; do not ex-
ceed 6 doses a day.
Overdosage
Usual overdose symptoms include breathing difficulties, nervousness progressing to stupor or coma, pinpointed pupils, cold clammy skin and lowered heart rate or blood pressure, nausea, vomiting, dizziness, ringing in the ears, flushing, sweating, and thirst. Symptoms of mild overdose include rapid and deep breathing, nausea, vomiting, dizziness, ringing or buzzing in the ears, flushing, sweating, thirst, headache, drowsiness, diarrhea, and rapid heartbeat. Severe overdose may cause fever, excitement, confusion, convulsions, liver or kidney failure, coma, or bleeding. Take the victim to a hospital emergency room immediately. ALWAYS bring the prescription bottle or container.
Special Information
This drug may cause drowsiness. Be careful when driving or performing any task that requires concentration.
Avoid alcohol while taking this drug.
If you have been taking this medication for more than a few weeks, do not stop taking it without your doctor’s instruction. Suddenly stopping this drug may lead to withdrawal symptoms.
Do not take this drug for longer or in amounts greater than prescribed.
Call your doctor if you experience breathing difficulties, or persistent nausea, vomiting, or constipation.
If you forget a dose, take it as soon as you remember. If it is almost time for your next dose, skip the one you forgot and continue with your regular schedule. Do not take a double dose.
For additional information see “Special Information” in Aspirin (page 110).
Special Populations
Pregnancy/Breast-teeding-. Fiorinal with Codeine should not be used during pregnancy. Pregnant women taking it may experience prolonged labor, delayed delivery, and bleeding problems. This drug increases the risk of birth defects and may cause breathing or bleeding problems in newborns. Regular use of Fiorinal with Codeine during the last 3 months of pregnancy may also cause drug dependency in the newborn.
Fiorinal with Codeine passes into breast milk. Breast-feeding while using this drug may cause tiredness, shortness of breath, or a slow heartbeat in the baby. Nursing mothers who must take this drug should use infant formula.
Seniors: This drug may have a greater depressant effect on seniors. Other effects that may be more prominent are stimulation, disorientation, lightheadedness, and dizziness or fainting when rising suddenly from a sitting or lying position.
Aug
12
Donnatal - Doxazosin - Doxercalciferol - Dronabinol - Dyazide
August 12, 2009 | Leave a Comment
Brand Name
Donnatal
Generic Ingredients
Atropine Sulfate + Hyoscyamine Sulfate + Phenobarbital + Scopolamine Hydrobromide EQ
Other Brand Names Antispas
Antispasmodic Barbidonna
Bellatal
Donnapine
Donnatal Extentabs Hyosophen Spasmolin
The information in this profile also applies V) the following drugs: Generic /nqcedjer)t: Hyoscyamine Sulfate 0
Anaspaz ED-SPAZ
A-Spas S/L Hyosol
Cytospaz Hyosyne
Donnamar IB-Stat
Levbid Levsin
Levsinex Timecaps Medispaz
DONNATAL
Neosol NuLev Spasdel Symax
Generic Ingredient: Propantheline 92 Pro-Banthine
Type of Drug
Anticholinergic combination.
Prescribed For
Stomach spasm and gastrointestinal (GI) cramps; also used to treat motion sickness.
General Information
Donnatal is a mild antispasmodic sedative. Its principal action is to counteract the effect of acetylcholine, an important neurohormone. Donnatal is used only to relieve symptoms. not to treat the underlying condition, and there is considerable doubt among medical experts that this drug lives up to its claims. In addition to the brand names listed above, there are about 50 other anticholinergic combinations with similar properties. All are used to relieve cramps and all are about equally effective. Some have additional ingredients to reduce or absorb excess gas in the stomach, to coat the stomach, or to control diarrhea. Donnatal and products like it should not be used for more than the temporary relief of symptoms.
Cautions and Warnings
Do not take Donnatal if you are allergic or sensitive to any of its ingredients.
Donnatal should not be used by people with glaucoma, rapid heartbeat, severe intestinal disease such as ulcerative colitis, intestinal obstruction, urinary difficulties, asthma, myasthenia gravis, acute intermittent porphyria, acute bleeding with unstable heart function, or hiatal hernia.
Phenobarbital may be, habit-forming and should not be admin(Ste_%16 10 people with a history of drug dependence.
Donnatal should be used with caution in children and in people with brain damage, spastic paralysis, Down’s syndrome, heart disease, high blood pressure, hyperthyroidism (overactive thyroid gland), kidney or liver disease, autonomic neuropathy, or gastric ulcer.
Donnatal can reduce your ability to sweat and may lead to heat exhaustion. Avoid extended heavy exercise and limit your exposure to high temperatures.
Possible Side Effects
♦ Most common: blurred vision, dry mouth, urinary difficulties, flushing, and dry skin.
♦ Less common: rapid or unusual heartbeat, increased sensitivity to bright light, loss of the sense of taste, headache, nervousness, tiredness, weakness, dizziness, sleeplessness, nausea, vomiting, fever, stuffy nose, heartburn, loss of sex drive, decreased sweating, constipation, feeling bloated, and allergic reactions such as fever and rash.
Drug Interactions
• Although Donnatal contains only a small amount of phenobarbital, it is wise to avoid alcohol or other sedative drugs. Although unlikely, phenobarbital interactions are possible with anticoagulants, adrenal corticosteroids, narcotics, sleeping pills, digitalis or other cardiac glycosides, and antihistamines.
• Some phenothiazine drugs, sedatives, tricyclic antidepressants, and narcotics may increase the side effects of the atropine sulfate ingredient in Donnatal, causing dry-mouth, urinary difficulties, and constipation. The effectiveness of phenothiazines to control psychotic symptoms may be decreased.
• Combining Donnatal and the antiviral amantadine may increase the side effects of Donnatal.
• Donnatal may increase the side effects of atenolol and digoxin.
• Antacids may decrease Donnatal’s effectiveness; do not take antacids within 1 hour of taking Donnatal.
Food Interactions
‘%ke Donnatal 30-60 minutes before meals.
Usual Dose
Donnatal
Adult (age 13 and over): 1-2 tablets, capsules, or tsp. 3-4 times a day, or 1 extended-release tablet every 12 hours.
Child (age 2-12): 112 the adult dosage. Child (under age 2): not recommended.
Propantheline
Adult-. 15 mg 3 times a day before meals, and 30 mg at bedtime. Senior: 7.5 mg 3 times a day.
Child (under age 12): not recommended.
Overdosage
Symptoms of overdose include dry mouth; difficulty swallowing; thirst; blurred vision; sensitivity to bright light; flushed, hot, or dry skin; rash; fever; abnormal heart rate; high blood pressure; urinary difficulties; restlessness; confusion; delirium; and breathing difficulties. The victim should be taken to a hospital emergency room immediately. ALWAYS bring the prescription bottle or container.
Special Information
Call your doctor if you experience persistent diarrhea, bloating, fever, heart palpitations, rash, flushing, or eye pain.
Do not crush or chew Donnatal tablets.
Dry mouth usually can be relieved by chewing gum or sucking hard candy or ice chips. Constipation can be treated with a stool-softening laxative.
Donnatal may reduce the amount of saliva in your mouth, making it easier for bacteria to grow there. Pay special attention to dental hygiene while taking this medication to prevent cavities and gum disease.
Donnatal may cause drowsiness and blurred vision. Be careful when driving or operating hazardous equipment.
If you forget to take a dose of Donnatal, take it as soon as you remember. If it is almost time for your next dose, skip the one you forgot and continue with your regular schedule. Do not take a double dose.
Special Populations
Pregnancy/Breast-feeding: Donnatal may cause drug dependency or breathing problems in newborns and may interfere with labor aM delivery. When this drug is considered crucial by your doctor, its potential must be carefully weighed against its risks.
Donnatal may pass into breast milk and may reduce the amount of milk produced. It may cause tiredness, shortness of breath, and a slower-than-normal heartbeat in infants. Nursing mothers who must take this medication should consider using infant formula.
Seniors: Seniors are often more sensitive to the side effects of Donnatal, such as excitement, confusion, drowsiness, agitation, constipation, dry mouth, and urinary difficulties. Memory may be impaired and glaucoma worsened.
Generic Name
Doxazosin (dok-SAY-zoe-sin) In
Brand Names
Cardura. Cardura XL
Type of Drug Antihypertensive.
Prescribed For
High blood pressure and benign prostatic hyperplasia (BPH); also used with digoxin and diuretic drugs to treat congestive heart failure.
General Information
Doxazosin mesylate and other alpha-adrenergic blocking agents, or alpha blockers, reduce blood pressure by dilating (widening) blood vessels. They achieve this effect by blocking nerve endings known as alpha, receptors. The maximum blood-pressurelowering effect of doxazosin is seen between 2 and 6 hours after taking a dose. In BPH treatment, doxazosin works by relaxing smooth muscles in the prostate and neck of the bladder. Doxazosin helps the symptoms of BPH, and taking it for several years may eliminate the need for surgery or allow the use of a less invasive type of surgery. Doxazosin’s effect lasts for 24 hours. It is mostly broken down in the liver; little passes out of the body via the kidneys.
Doxazosin may slightly reduce cholesterol levels and improve the ratio of high-density lipoprotein (HDL)—”good” cholestemAand low-density lipoprotein (ILDL}—”bad cholesterol”—a positive step for peQ¢kp_%Aln a blood-cholesterol problem.
Cautions and Warnings
Do not take doxazosin if you are allergic or sensitive to any of its ingredients or to any alpha blocker.
Doxazosin may cause dizziness and fainting, especially the first few doses. This is known as a first-dose effect, which can be minimized by limiting the first dose to 1 mg at bedtime. First-dose effects occur in about i % of people taking an alpha blocker and may recur if the drug is stopped for a few days and then started
again.
Doxazosin should be taken with caution if you have liver
disease.
White-blood-cell counts may be slightly decreased in people
taking doxazosin.
Rarely, alpha blockers, including doxazosin, have led to pri-
apism (painful and prolonged erection). Call your doctor immediately if this happens. If not treated promptly, this condition can lead to impotence.
Possible Side Effects
✓ Most common: headache, dizziness, and weakness.
♦ Less common: heart palpitations, abnormal heart rhythms, chest pain, nausea, diarrhea, constipation, abdominal pain or discomfort, gas, breathing difficulties, nosebleed, sore throat, runny nose, muscle or joint pain, visual disturbances, conjunctivitis (pinkeye), ringing in the ears, fainting, depression, decreased sex drive or sexual function, tingling in the hands or feet, nervousness, tiredness, anxiety, sleeplessness, poor muscle coordination, muscle stiffness, poor bladder control, frequent urination, itching, rash, sweating, fluid retention, facial swelling and flushing, and back, neck, shoulder, arm, or leg pain.
✓ Rare: vomiting, dry mouth, sinus irritation, bronchitis, cold or flu symptoms, worsening of asthma, coughing, hair loss, weight gain, and fever. Contact your doctor if you experience any side effect not listed above.
Drug Interactions
• Doxazosin may interact with beta blockers to ‘increase the risk of dizziness or fa:kv%1)g alter the first dose of doxazosin.
• TW-1 UDOd-pressure-lowering effect of doxazosin may be reduced by indomethacin.
• When taken with other blood-pressure-lowering drugs, dox-
azosin produces a severe reduction of blood pressure.
• The blood-pressure-lowering effect of clonidine may be reduced by doxazosin.
Doxazosin should be taken with caution in combination with clarithromycin, ketoconazole, and itraconazole.
Food Interactions None known.
Usual Dose
Adult: 1 mg morning or evening to start; may be increased to a total of 16 mg, taken once a day. Extended-release tablets-4 mg once daily at breakfast; may be increased to a total of 8 mg. Do not chew, cut, or crush extended-release tablets.
Child: not recommended.
Overdosage
Overdose may produce drowsiness, poor reflexes, and very low blood pressure. Overdose victims should be taken to a hospital emergency room at once. ALWAYS bring the prescription bottle or container.
Special Information
Take doxazosin exactly as prescribed. Do not stop taking it unless directed to do so by your doctor. Avoid over-the-counter drugs that contain stimulants because they may increase your blood pressure.
Doxazosin may cause dizziness, headache, and drowsiness, especially 2-6 hours after you take your first dose, although these effects can persist after the first few doses. Use caution when getting up from a sitting or lying position.
Call your doctor if you develop severe dizziness, heart palpitations, or any bothersome or persistent side effect.
Wait 12-24 hours after taking your first dose of doxazosin before driving or doing anything that requires concentration. Take your dose at bedtime to minimize this problem.
If you forget a dose, take it as soon as you remember. If it is almost time for your next dose, skip the dose you forgot and coT)- tinue with your regular schedule. Do R(ak%’Ke a double dose.
4VIWIal Populations
Pregnancy/Breast-feeding: The safety of using doxazosin during pregnancy is not known, although animal studies have shown that alpha blockers may affect fetal development. When this drug is considered crucial by your doctor, its potential benefits must be carefully weighed against its risks.
Small amounts of doxazosin pass into breast milk. Nursing mothers who must take this drug should use infant formula.
Seniors: Seniors, especially those with liver disease, may be more sensitive to the effects and side effects of doxazosin.
Generic Name
Doxercalciferol (dox-er-kal-Sffl-fer-ahl)
Brand Names
Drisdol Liquid Hectorol Capsules
Type of Drug
Vitamin D supplement.
Prescribed For
Elevated parathyroid hormone levels in patients undergoing kidney dialysis.
General Information
Doxercalciferol is a synthetic form of vitamin D that is processed in the body to form active vitamin D. Vitamin D, along with parathyroid hormone, are key elements of the calcium-regulating system in the body. Normally, your body releases parathyroid hormone if blood calcium levels are too low. Parathyroid hormones move calcium from the place where it is found in greatest quantity—your bones—into the bloodstream. This can have disastrous effects for a wide variety of body functions where calcium is crucial including muscle contraction, nervous system function, bone fragility, and blood clotting. Doxercalciferol helps to stabilize the system and normalize parathyroid hormone levels that can be artificially elevated in dialysis patients.
Cautions and Warnings
Do not use doxercalciferol if you are allergic or sensitive to any of its ingredients.
Do not take any other Vitamin D supplement while taking this dwg.
People with a tendency toward high calcium or vitamin D levels should not take doxercalciferol.
Before taking this medication, tell your doctor if you have liver disease. You may not be able to take doxercalciferol, or you may require a dosage adjustment or special monitoring during treatment.
Dialysis patients experience increases in blood calcium and phosphate while taking this drug.
Drug Interactions
• Do not take antacids that contain magnesium while you are taking doxercalciferol.
• Cholestyramine may reduce the absorption of doxercalciferol.
• Prolonged use of mineral oil may reduce the absorption of doxercalciferol.
• Do not combine any other over-the-counter or prescription medicines, or vitamin supplements with doxercalciferol without first talking with your doctor.
• The following medicines can slow the transformation of doxercalciferol to its active form in the body, reducing its effectiveness: ketoconazole, erythromycin, delaviridine, indinavir, nelfinavir, ritonavir, amiodarone, aprepitant, chloramphenicol, cimetidine, ciprofloxacin, clarithromycin, diltiazem, fluconazole, fluvoxamine, gestodene, itraconazole, mifepristone, nefazodone, norfloxacin, mibefradil, and verapamil.
• The following drugs can increase the breakdown of doxercalciferol in the liver, possibly reducing its effectiveness: efavirenz, nevirapine, barbiturates, carbamazepine, glucocorticoids, modafinil, phenobarbital, phenytoin, rifampin, St. John’s wort, oxcarbazepine, pioglitazone, and rifabutin. Dosage adjustment may be needed.
• Digoxin may cause symptoms of alcohol intolerance when combined with disulfiram or mettot)idazole.
Food (”WTactions
Avoid grapefruit products as they can slow the transformation of doxercalciferol to its active form in the body, reducing its effectiveness.
You may need to limit your consumption of foods containing vitamin D. Consult your doctor.
constipation, general discomfort, nausea, difficulty breathing, and itching.
of appetite, indigestion, weight gain, on, sleepiness, and slowed heart rate.
Possible Side Effects
♦ Common: swelling, headache, dizziness,
✓ Less common: loss joint pain,
Usual Dose
Adult:starting dose-10 mcg 3 times a week during kidney dialysis treatment. Dosage may be adjusted to 2.5 mcg at 8-week in-
tervals if necessary.
Child: not recommended.
Overdosage
Symptoms include weakness, headache, drowsiness, nausea, vomiting, dry mouth, metallic taste in mouth, constipation, muscle pain, bone pain, and irregular heartbeat. Call your local poison control center or a hospital emergency room for more information. It you seek treatment, ALWAYS bring the prescription bottle or container.
Special Information
Compliance with dosage instruction, diet, and calcium supplementation is important while taking doxercalciferol.
Lab tests are required to monitor therapy while taking doxercalciferol.
Doxercalciferol may cause dizziness. Use caution while driving or performing other tasks requiring alertness, coordination, or physical dexterity.
Special Populations
Tell your doctor or pharmacist if you are pregnant, planning on becoming pregnant, or breast-feeding.
The safety of using doxercalciferol during pregnancy is not known. When this drug is considered crucial by your doctor, its potential benefits must be carefully weighed against its risks.
It is not known if doxercalciferol passes into breast milk. Nursing mothers who must use this drug should use infant formula.
Seniors: Seniors may use this drug without special precaution.
Generic Name
Dronabinol (droe-Mla-ih,bl)
Brand Name Marino)
Type of Drug Antinauseant.
Prescribed For
Nausea and vomiting associated with cancer chemotherapy, and appetite stimulation and weight-loss prevention in people with acquired immunodeficiency syndrome (AIDS).
General Information
Dronabinol is a legal form of marijuana. The psychoactive chemical in marijuana is delta-9-THC. Dronabinol has all of the psychological effects of marijuana and is therefore considered to be a highly abusable drug. It can cause personality changes, feelings of detachment, hallucinations, and euphoria (feeling “high”). Younger adults have reported a greater success rate with dronabinol, probably because they are better able to tolerate these effects.
Most people start taking dronabinol while in the hospital so their response to the drug and its possible adverse effects can be monitored. Dronabinol has also been studied as a glaucoma treatment.
Cautions and Warnings
Do not take dronabinol if you are allergic or sensitive to any of its ingredients, to marijuana, or to sesame oil.
Dronabinol should not be used to treat nausea and vomiting caused by anything other than cancer chemotherapy.
Dronabinol should be used with caution in those with a history of seizure disorders or substance abuse.
Dronabinol has a profound effect on mental states; it will impair your ability to operate complex equipment or engage in any activity that requires intense concentration, sound judgment, or coordination—such as driving a car.
Dronabinol produces withdrawal symptoms when the drug is stopped. These may develop within 12 hours of the drug’s discontinuation and include restlessness, sleeplessness, and irritability. Within a day after the drug has been stopped, stuffy nose, hot flashes, sweating, loose stools, hiccups, or appetite loss may occur. The symptoms usually subside within a few days,
Dronabinol should be used with caution by people with heart disease or high blood pressure. Dronabinol should be used with caution by people with a manic-depressive or schizophrenic history because it may aggravate the underlying disease.
Possible Side Effects
V Most common: drowsiness, euphoria, dizziness, anxiety, muddled thinking, perceptual difficulties, poor coordination, irritability, a separation in time and space, depression, weakness, sluggishness, nausea and vomiting, headache, hallucinations, memory lapses, loss of muscle coordination, unsteadiness, paranoia, depersonalization, disorientation, confusion, rapid heartbeat, and dizziness when rising from a sitting or lying position.
♦ Less common: difficulty talking or slurred speech, facial flushing, excessive perspiration, nightmares, ringing or buzzing in the ears, fainting, diarrhea, loss of bowel control, and muscle pain.
Drug Interactions
• Dronabinol increases the effects of alcohol, sleeping pills, sedatives, and other depressants. It also enhances the effects of psychoactive drugs including tricyclic antidepressants, amphetamines, cocaine, and other stimulants.
• Dronabinol may increase the effects of fluoxetine and disulfiram.
• The effects of theophylline drugs are reduced by dronabinol.
• Combining dronabinol and antihistamines or anticholinergic drugs may cause either rapid heartbeat or excessive drowsiness.
Food Interactions
This drug may be taken without regard to food or meals; as an appetite stimulant, it is often taken before meals.
Usual Dose
Antiemetic: 5 mg 1-3 hours before starting chemotherapy treatment and repeated every 2-4 hours after treatment, for a total of 4-6 doses a day. Dosage may be increased up to 15 mg per dose if needed; psychiatric side effects increase greatly at higher dosages.
Appetite Stimulant: 2.5 mg before lunch or dinner, or 2.5 mg at bedtime. Dosage may be increased to 20 mg a day.
Overdosage
Overdose symptoms may occur at usual dosages or at higher dosages if the drug is being abused. The primary symptoms of
overdose are the psychological symptoms listed above (see “Possible Side Effects”). In some cases, overdose may lead to panic reactions or seizure. Contact a hospital or local poison center for more information. If you seek treatment, ALWAYS bring the prescription bottle or container.
Special Information
Be careful when driving or performing any task that requires concentration. Avoid alcohol and other central nervous system (CNS) depressants.
Dronabinol may cause acute psychiatric or psychological side effects. Call your doctor if any develop.
The capsules must be stored in the refrigerator.
If you forget a dose, take it as soon as you remember. If it is almost time for your next dose, skip the one you forgot and continue with your regular schedule. Do not take a double dose.
Special Populations
Pregnancy/Breast-feeding; Animal studies have shown adverse effects on the fetus. When this drug is considered crucial by your doctor, its benefits must be carefully weighed against its risks.
Dronabinol passes into breast milk. Nursing mothers who must take this drug should use infant formula.
Seniors: Seniors may be more sensitive to this drug, especially its psychological effects.
Brand Name
Dyazide
Generic Ingredients Hydrochlorothiazide + Triamterene 5§1
Other Brand Names
Maxzide Maxzide-25
The information in this 10TOVile also applies to the following drugs:
Generic Ingredients: Amiloride + Hydrochlorothiazide 92 Hydro-Ride Moduretic
Generic Ingredients: Spironolactone + Hydrochlorothiazide KI
Aldactazide Spironazide
Alzide Novo-Spirozine Spirozide
Type of Drug
Diuretic that increases urination).
Prescribed For Hypertension (high blood pressure) or any condition where it is de-
sirable to eliminate excess water from the body. General Information
Dyazide combines a thiazide diuretic and a potassium-sparing diuretic. The latter, triamterene, helps the body retain potassium while producing a diuretic effect. This balances the other ingredient, hydrochlorothiazide, which normally causes a loss of potas- sium. Different products contain differing concentrations of these 2 drugs. Dyazide should be used only when you need its exact proportion of ingredients, and should not be used for initial therapy of hypertension or edema. It may be used alone or with other anti hypertensive drugs such as beta blockers. Dosage adjustment may be necessary.
Cautions and Warnings
Do not use dyazide if you are allergic or sensitive to any of its ingredients or to any sulfa drug or if you have a history of allergy.
Do not use Dyazide if you have nonfunctioning kidneys, bronchial asthma, or hyperkalemia (high blood potassium levels).
Do not combine any potassium supplement and Dyazide without your doctor’s knowledge. Dyazide may reduce blood levels of sodium and potassium and raise blood calcium levels.
Dyazide should be used with caution in people with diabetes, liver disease, or an electrolyte imbalance.
Possible Side Effects
♦ Most common: appetite loss, drowsiness, lethargy, head-
ache, gastrointestinal upset, cramping, and diarrhea.
V Less common: rash—possibly severe, mental confusion, fever, feeling unwell, impotence, bright red tongue, burnt”g sensation in the tongue, tingling in the toes and fingers, restlessness, anemia or other effects on blood components, increased sensitivity to sunlight, and dizziness when rising quickly from a sitting position. Dyazide may also produce muscle spasms, gout, weakness, and blurred vision.
Drug Interactions
other blood pressure
• Dyazide increases the effect of
drugs. This is why other blood-pressure drugs are often prescribed with Dyazide, but dosage adjustments may be required.
• Combining Dyazide and digitalis drugs, amphotericin B, or adrenal corticosteroids increases the risk of body-fluid imbalance. If you are taking insulin or an oral antidiabetic drug and begin taking Dyazide, the insulin or antidiabetic dosage may have to be modified.
• Dyazide may increase the risk of allopurinol side effects.
• Dyazide may decrease the effects of oral anticoagulant (blood-thinning) drugs.
• Antigout drug dosage may have to be modified since Dyazide raises uric-acid levels.
• Dyazide may prolong the effects of chemotherapy drugs on reducing white-blood-cell counts.
• Dyazide may increase the effects of diazoxide, which may lead to symptoms of diabetes.
• Dyazide should not be taken with loop diuretics because the combination can lead to an extreme diuretic effect and an extreme effect on blood-sodium levels.
• Dyazide may increase the effect of vitamin D, which may cause high blood-calcium levels.
• Propantheline and other anticholinergics may increase the diuretic effect of Dyazide.
• Lithium carbonate taken with Dyazide should be monitored carefully by a doctor due to an increased risk of lithium side effects.
• Cholestyramine and colestipol prevent Dyazide from being absorbed. Dyazide should be taken at least 2 hours before cholestyramine or colestipol.
• Methenamine and other urinary agents may reduce the effect of Dyazide.
• Some nonsteroidal anti-inflammatory drugs (NSNDs), particularly indomethacin, may reduce the effect of Dyazide. Sulindac, another NSAID, may increase its effect.
• Potassium-sparing diuretics should be used with caution in combination with ACE inhibitors.
Food Interactions
Take this drug with food if it upsets your stomach.
usual Dose
Adult
Amiloride combination: 1-2 tablets daily with meals.
Spironolactone combination: 1-8 tablets daily.
Triamterene combination: 1-2 capsules or tablets a day. Child: not recommended.
Overdosage
Symptoms may include tingling in the arms or legs, weakness, fatigue, changes in heartbeat, a sickly feeling, dry mouth, restlessness, muscle pain or cramps, urinary difficulties, nausea, and vomiting. In some cases, low blood pressure and decreased respiration may occur. Take the victim to a hospital emergency room immediately. ALWAYS bring the prescription bottle or container.
Special Information
Dyazide causes excess urination at first, but this subsides after several weeks of use. Diuretics are usually taken early in the day to prevent excessive nighttime urination that may interfere with sleep.
Dyazide may make you drowsy. Be careful when driving or performing any task that requires concentration.
Call your doctor if you develop muscle pain, sudden joint pain, weakness, cramps, nausea, vomiting, restlessness, excessive thirst, tiredness, drowsiness, increased heart or pulse rate, diarrhea, dizziness, headache, or rash.
People with diabetes may experience an increased blood-sugar level and require dosage adjustments of their antidiabetic medications.
Avoid other drugs while taking Dyazide unless otherwise directed by your doctor. Avoid alcohol.
If you are taking Dyazide for the treatment of hypertension or congestive heart failure (CHF), avoid over-the-counter cough, cold, or allergy medications, which may contain Ft%m\)%an1s.
Take Dyazide exactly -as prescribed. Be aware that all triarRtt~tl)Z-’hydrochlorothiazide products are not equal to each other and should not be freely substituted. Check with your doctor and pharmacist before switching brands.
If you forget a dose, take it as soon as you remember. If it is almost time for your next dose, skip the dose you forgot and continue with your regular schedule. Do not take a double dose.