Jul
17
Cytotec (Misoprostol)
July 17, 2011 | Leave a Comment
Buy Cytotec without a prescription online at a cheap price. Order generic Cytotec (Misoprostol) without rx in internet pharmacy. Purchase cheap Cytotec 100 mcg, 200 mcg.
Oral tablets of Cytotec contain either 100 mcg or 200 mcg of the active ingredient Misoprostol. Buy Cytotec at online pharmacies without prescription. Purchase low cost Misoprostol online and get it shipped to you on the same day. Order Cytotec online and allow a few days after you have placed your order, as it may take you several business days to receive your online purchased Cytotec (Misoprostol).You need to see your doctor for a specialist’s advice on how you should take Cytotec, its side effects, interaction and contradictions. Please note that, to prevent the possible danger of the drug misuse, it is not advised to start taking your Cytotec or Misoprostol, ordered online without prescription, before consulting your doctor. Try to come clear on what your shoud order online: Cytotec 100 mcg or Cytotec 200 mcg. Make sure that you avoid a mistake of buying the cheaper Cytotec 100 mcg, and thus taking an insufficient dosage. It is important to mind your correct dosage, and possible allergic reactions when you take any drug, including Misoprostol. Make sure you are not allergic to it. Avoid taking Cytotec during pregnancy, as it is known to be very dangerous for an unborn baby. So if you become pregnant during treatment with Misoprostol, immediately stop taking it and consult your doctor. Do not share your Misoprostol with anybody else, especially with women of childbearing potential, as unauthorised use of Misoprostol in such persons may be extremely dangerous.
Generic Cytotec, Misoprostol, has the same chemical formula, quality, and is as effective as brand Cytotec. There is not much difference between those two medications, except for the difference in price. Buy lower cost generic Cytotec, if you are looking for a budget price. Both Cytotec and Misoprostol are widely prescribed by medical authorities woldwide. Yet there is no need to obtain a prescription in order to purchase this medication. In case you do not have a prescription, you still can get your no prescription Misoprostol as well as no prescription Cytotec online. Get generic Cytotec online and save, as there it is sold few times cheaper then in regular pharmacies. Order generic Cytotec (Misoprostol) without prescription from the comfort of your home, using the popular payment methods. It will take you just a few clicks, and your purchase is on the way. Cheap internet price of Misoprostol and fast delivery makes it a popular way of purchasing this med.
Enter Here to Buy Cytotec (Misoprostol)
Jul
17
Celebrex (Celecoxib)
July 17, 2011 | Leave a Comment
Buy Celebrex without a prescription online at a cheap price. Order generic Celebrex (Celecoxib) without rx in internet pharmacy. Purchase cheap Celebrex 100 mg, 200 mg.
Celebrex is a brand of Celecoxib - a popular pain-killer medication. Celebrex provides pain relief for both acute and chronic pains, and it is manufactured in dosages of 100 mg and 200 mg. Buy cheap Celebrex at online pharmacy without prescription. It is possible to order online any amount of low price Celebrex without prescription. Get a considerable discount when purchasing larger amount of this medication. Note that though you can purchase Celebrex without a prescription, yet consult a doctor before taking it. Tell your doctor about all medications you are using, as you need to avoid mixing up drugs while taking Celebrex. Avoid using any other cold, pain, or allergy medicine together with your no rx Celebrex. Medicines similar to Celecoxib can be met in many combination drugs. Do not take Celebrex for longer then recommended. In case you have a prescription, read it carefully prior to taking the med, and follow the directions. Do not overdose. Overdose of Celecoxib may result in nausea, stomach pain, vomiting, and fainting. This illustrates why is it so important to consult your doctor, before you take Celebrex without prescription, who will provide you with detailed information on how to take it, your personal dosage, duration of treatment as well as possible interactions, contraindications and side effects. Get Celebrex without prescription, make sure to consult your doctor, and take your Celebrex 100 mg or Celebrex 200 mg exactly as prescribed. Use it correctly and avoid possible side effects.
Buying Celecoxib, please mind, that cheap generic Celebrex is an identical drug with a brand medication and they have similar effectiveness, chemical formula, and both are approved by medical authorities for manufacture and sale. Celebrex is widely available both in the regular and online pharmacies. Prices may vary, yet, when you order cheap generic Celebrex from an online pharmacy, it seems to be the best deal. Get generic Celecoxib online without a prescription at a lower cost then the cost of the same medication at your local pharmacy. You would pay for your purchase with one of the popular electronic payment methods. Order cheap Celebrex online without prescription, it is usually shipped on the same day and delivered to you in a couple of days.
Enter Here to Buy Celebrex (Celecoxib)
Jul
16
Clomid (Clomiphene)
July 16, 2011 | Leave a Comment
Buy Clomid without a prescription online at a cheap internet generic pharmacy. Order generic Clomid without RX on line at an affordable cost and no prescription. Purchase Clomid (Clomiphene) 100 mg, 25 mg, 50 mg mg for infertility treatment.
Clomid is a an extremely popular and widely prescribed medication for the treatment of infertility problem with women. Clomid (Clomiphene) has shown effective results with the patients and is prescribed to millions of women around the world. Buy Clomid on line without prescription and save considerable amount of money purchasing cheaper generic Clomid at online pharmacy without rx or visiting a doctor. Generic Clomid is Clomiphene and it is an active ingredient of the drug. Generic Clomid has no difference from a brand one having the same chemical formula, active ingredients, effectiveness, quality and full approval for manufacture and sale. Order Clomid online from the comfort of your own home and start your treatment course within several working days upon receipt of your Clomiphene order. Online pharmacy offers generic drus at affordable prices without a prescription, various bonuses and discounts are applied like free shipping of bigger orders, discount for all the returning orders and cheaper pill prices for bigger amounts.
Prior to purchasing Clomid consult your doctor who will inform you about this drug action, length of the treatment course, your personal dosage, possible interactions and side effects as well as other general patient`s information about Clomiphene (generic Clomid). Clomid is manufactured in tablets 100 mg, 50 mg and 25 mg. Price per pill when ordering Clomid will depend on the dosage (for example, Clomid 50 mg is cheaper than Clomid 50 mg), so it is important to check it before making an order. Buy generic Clomid online without rx cheap from the trustable and secure on line pharmacy using the popular payment methods such as Visa, Master Card and Amex. Choose between Clomid 100 mg, 50 mg or 25 mg and make a secure order online. Cheap Clomid without prescription internet order is a great both money and time saver which makes online generic drugs purchase a popular method of getting prescription medications without a prescription. Where to buy Clomid cheap online without prescription? Just follow the link below to enter a pharmacy website selling affordable generics.
Enter Here to Buy Clomid (Clomiphene)
Jul
10
Proventil (Albuterol)
July 10, 2011 | Leave a Comment
Buy Proventil without a prescription online at a cheap price. Order generic Proventil (Albuterol) without rx in internet pharmacy. Purchase Proventil 100 mcg astma treatment drug at a discounted price.
Proventil is a drug for the treatment or prevention of bronchospasms and is prescribed to millions of patients worldwide showing very good results and having positive records. Buy generic Proventil online without a prescription from the comfort of your home at a really cheap price that can be up to 5 times lower than Proventil cost from a regular pharmacy offline. Generic Proventil Albuterol has no difference from the brand version of this drug having the same chemical formula, effectiveness and side effects and being fully approved by medical authorities for manufacture and sale worldwide. Buy Proventil cheap online and save bot your time and money, because Proventil from internet pharmacy is cheap and there is no need to get a prescription in order to purchase this drug online. Cheap Proventil is a great money saver and there are further discounts applied for all the next generic drugs orders for both Albuterol and all the other drugs from the big list of more than 500 popular names available to get online without rx. You will get a 10% discount for all the further orders and free delivery starting from $200 orders.
Before buying Proventil you should consult a doctor to find out if this drug is indicated for the treatment of your symthoms as well as other information such as side effects, contraindications, interactions with other medications, how to take Proventil etc. The dosage of Proventil available to buy online without a prescription is 100 mcg. It is easy to buy Proventil online without a prescription in generic version from the comfort of your home using all the popular payment methods such as visa, mastercard and amex. Purchasing Proventil without rx from overseas pharmacy is legal, because Albuterol is not in the list of controlled substances. If you need Proventil or ask can I buy no prescription Proventil online or just need more information on this popular asthma treatment drug just follow the link below and enter online pharmacy delling cheap generic drugs without prescription with fast worldwide delivery.
Enter Here to Buy Proventil (Albuterol)
Jul
10
Seroquel (Quetiapine)
July 10, 2011 | Leave a Comment
Buy Seroquel without a prescription online at a cheap price. Order generic Seroquel (Quetiapine) 25 mg, 50 mg, 100 mg, 200 mg, 300 mg without rx and get your order delivered fast. Cheap Seroquel online is for sale without a prescription. Purchase Seroquel with fast delivery worldwide.
Seroquel is a drug for depression treatment (antidepressant) and is prescribed to millions of patients worldwide every year. Buy generic Seroquel online without a prescription from a reliable internet pharmacy selling generic drugs at a cheap price. Cheap Seroquel generic version is the same drug as a brand one having the same chemical formula, effectiveness and quality and are fully approved for manufacture and sale. It is legal to buy Seroquel without a prescription online, because the medication is not on the list of controlled substances and you are ordering it from an overseas pharmacy. Generic Seroquel online can be ordered without rx and its price is up to 5 times lower than the cost of brand one. These are the advantages of buying generic meds on line which is enjoyed by thousands of people who do not want to pay much for overpriced medication at a regular pharmacy, spend time visiting a doctor or just leave home to go to a pharmacy shop.
When ordering online Seroquel, keep in mind that the order price will depend on the quantity of pills you are buying (the more you buy, the cheaper the total order cost is going to be). Generic Seroquel dosages per pill available to buy are 25 mg, 50 mg, 100 mg, 200 mg, 300 mg. Price per pill depends on the dosage (for example, Seroquel 50 mg is cheaper than Seroquel 200 mg or 300 mg). There are more discounts applied - 10% discount for all the refill orders for both Quetiapine and all the other meds from online generic pharmacy where you can get pills without prescription cheap. Before buying Seroquel online, consult your doctor to learn your personal per pill dosage, how to take Seroquel, possible side effects and interactions. After that you can go online and buy Seroquel cheap from the comfort of your own home. Depression treatment drugs are serious medications and usually requiry a prolonged course and it is advisable not to give up taking antidepressunts suddenly without the course completion. This is why it makes sense to order enough no prescription Seroquel so that not to run out of pillse in the middle of your course. If you want to buy Seroquel without prescription or need more information about this drug, just follow the link below to enter an online pharmacy selling generic drugs at cheap cost.
Enter Here to Buy Seroquel (Quetiapine)
Jul
10
Vermox (Mebendazole)
July 10, 2011 | Leave a Comment
Buy Vermox online without a prescription. Generic Vermox (Mebendazole) without rx at a cheap price. Order Vermox 100 mg online cheap at low discounted price at internet pharmacy.
Vermox is a drug for the treatment of worms infection symthoms and is prescribed to millions of patients worldwide annually. Buy generic Vermox online without a prescription without the need to visit a doctor or just leave your home. Online cheap Vermox has a price up to 5 times lower than the same medicine purchased from a regular pharmacy, being at the same time 100% identical with the brand one as far as its chemical formula, effectiveness and quality are concerned and generic Vermox is fully approved by medical authorities. Cheap Vermox is a popular money saver for many patients who enjoy low prices of generic online drugs making orders online at a discount pharmacy.
Prior to purchasing Vermox Mebendazone online without rx at a cheap price, it is a good idea to consult a doctor who will give a patient full instrucion how to take this drug, information about its possible side effects, interactions and precautions as well as any other general patient`s data. After that you can order cheap Vermox on line without the need to obtain a prescription using convenient payment methods such as Visa, MasterCard and Amex. Vermox order will be shipped the same day and you will get you Mebendazole pills within several working days delivered to your door. Further 10% discount is applied for any other refill orders both for generic Vermox 100 mg and all the other medications from the huge list of 500 drugs for sale online without a prescription cheap.
Buy Vermox (Mebendazole) in the amount you require for your treatment, because the order price depends on the quantity of pills you are purchasing (the more you buy the lower the total cost will be). No prescription Vermox is cheap, available without rx online and there are more discounts and bonuses applied when buying generic drugs from a low price internet pharmacy. Vermox 100 mg is the only dosage of the drug available for sale and it is the most popular one on the market today and prescribed by doctors. Order Vermox online cheap and save both time and money. If you are interested, please, follow the link below to get the drug or just receive more information on buying Vermox as well as all the rest of the medications.
Enter Here to Buy Vermox (Mebendazole)
May
30
Generic Drugs: Is There a Difference Between Generic Drugs and Brand?
May 30, 2011 | Leave a Comment
Before patients buy generic drugs online they want to know the answers to some of their questions, regarding generics. Why can one buy generic drugs cheap? Are generic drugs effective? Where can I buy generic drugs without a prescription cheap?
Today a lot of online pharmacies offer cheap generic drugs without a prescription and thousands of patients around the world take the opportunity to save on very expensive brand medications from a local pharmacy store. Generics are full analogues of brand ones, but are available to order online cheaper. Online pharmacies sell some drugs without a prescription which makes generic drugs purchase online even more convenient as you do not have to see a doctor.
Patients of all age groups and walks of life want to be treated effective and quality medicine. But here’s to suit all your medicines in different ways: some prefer to buy expensive original drugs, while others believe that lower-cost counterparts in no way inferior to well-known brands. In short, demand is there for any kind of drugs, as ill and eating a man does not stop never. What to and enjoy all kinds of pharmaceutical companies, letting the world market many drugs under various trade names.
According to recent statistics, the proportion of generic counterparts of drugs (generics) in the markets of many countries will only increase. Although the dynamics of growth is not the same: if the U.S. resorted to the use of generic drugs in approximately 15% of the treatment of diseases in Europe - 40-50%, in the post-Soviet countries - up to 80-90%. But do not be afraid of these numbers. Because generic - a quality product, which according to its pharmacological data of the original copies. The active substance in the analog and the original is absolutely identical. But the price of drugs is much different. And obviously for the benefit of generics. Why is this happening? To do this, to understand the differences in the production of both options medication.
When a pharmaceutical company synthesized a new drug, it is patent the name and performs a full spectrum of possible research - from clinical to experimental. Their progress is determined by: the exact formula, the effectiveness of the drug and all its side effects. At this preliminary stage can take up to 10 years. If we consider that a patent for the drug is given by an average of 20 years (sometimes 25), then for the remaining 10-15 years “exclusive use” producer has to invest heavily in the campaign, so with the help of massive purchases “recapture” the cost of wasted millions to test and make a profit. It is clear that the original price of such drugs will be essential.
What happens after the expiration of a patent? Right to manufacture the same drug, but under a different name may acquire any other company. Since emerging on the market, for example, not nootropil, and piracetam. This medicine is an exact copy of an analog, but since its production has already spent far less money, and it determines the selling price, which is an order of magnitude lower. So the generic - a kind of high-quality tracing paper once a patented drug, but at an affordable cost for a wide range of customers.
Dzhenericheskie drugs all over the world before they go on sale are thoroughly tested for compliance with the equivalence of the original drug. Such a study is conducted in three areas:
Pharmaceuticals - medicines should:
contain the same active ingredients;
introduced an identical manner;
be similar in concentration and its effect on the body.
Biological - the deviation between the analogs and copies are allowed no more than 15-20% of such parameters:
period of drug intake;
time to reach maximum concentration;
type and duration of excretion from the body.
Clinical - generic shall match the original for these indicators:
active substance;
security;
efficiency.
Thus, the generic is a quality drug, which contains the same active ingredient as the original drug, same adjuvants and production technology.
Summarizing the above, conclusions can be drawn: the use of generic drugs is absolutely justified, since it gives the doctor and patient choice; can treat almost all people from different walks of life, available in a price range, efficient and safe. In addition, taking a growing niche market of medicines, generic drugs stimulate the company’s original look promising new directions in drug development.
Tags: active ingredients, age groups, buy generics online, counterparts, different ways, drugs, drugs without a prescription, effectiveness, formula, GENERIC, Generic drugs, generic drugs cheap, generic drugs online, generics, Ingredients, medication, Medications, online pharmacies, online pharmacy selling generic drugs, order, pharmaceutical companies, pharmaceutical company, pharmacy, pharmacy store, prescription drugs, production, proportion, purchase generic drugs, quality medicine, quality product, Research, soviet countries, substance, trade names, Treatment, world marketMay
26
Diuretics
May 26, 2011 | Leave a Comment
Diuretics
COMMON DIURETICS
• Bendroflumethiazide (Naturetin)
• Benzthiazide (Exna)
• Bumetanide (Bumex)
• Chlorothiazide (Diuril, Diachlor, Diurigen)
• Chlorthalidone (Hygroton)
• Ethacrynic acid (Edecrin)
• Furosemide (Lasix)
• Hydrochlorothiazide (Esidrix, HCTZ, HydroDIURIL, Oretic)
• Hydroflumethiazide (Diucardin)
• Indapamide (Lozol)
• Methyclothiazide (Aquatensen, Enduron)
• Polythiazide (Renese)
• Trichlormethiazide (Diurese, Metahydrin, Naqua)
The first real breakthrough in the treatment of high blood pressure occurred in 1958. That was when chlorothiazide was introduced. Before this “thiazide” diuretic was developed, physicians admonished patients to eliminate salt from their diets. It was one of their few treatment options and was only partially effective. Other available drugs like reserpine, which was derived from the Rauwolfia serpentine plant, often caused very serious side effects such as suicidal depression.
Although chlorothiazide and similar compounds started a revolution in blood pressure treatment, they eventually lost their luster. Newer medications like beta-blockers, calcium channel blockers, and ACE inhibitors seemed sexier and more powerful. Since diuretics were old and available generically, drug companies promoted the new, more expensive products. And physicians responded by prescribing Tenormin (atenolol) or Procardia (nifedipine). We now know that such drugs are not better and may even be worse than old-fashioned, unglamorous diuretics. This government-sponsored study, which cost $120 million, tracked more than 40,000 subjects for years to determine the outcomes of various blood pressure–lowering drugs scientists found that chlorthalidone, an inexpensive diuretic, was superior to some popular brand-name blood pressure pills.
The pharmaceutical industry had spent billions investigating and promoting products like Norvasc (amlodipine), Cardura (doxazosin), and Prinivil (lisinopril). For FDA approval, drug companies need only prove that a medicine lowers blood pressure more effectively than placebo. They have little incentive to test medications head-to-head to determine how
they compare in improving health.
That’s what makes this government research so important. Instead of just looking at numbers on a blood pressure monitor, scientists determined whether people had suffered heart attacks, strokes, or heart failure or had died. Curt Furberg, MD, PhD, chair of the study’s steering committee, shared his conclusions with us: “It’s important to lower blood pressure, but it matters how you do it. The diuretics have three advantages. They are unsurpassed in lowering blood pressure; they are superior in reducing the cardiovascular complications of hypertension; and they are 10 to 20 times cheaper than the newer branded drugs.” Doctors were probably astonished to learn that in this trial the alpha-blocker Cardura (doxazosin) actually increased the likelihood of heart failure compared with diuretic treatment.
Chlorthalidone
Many physicians believe that all thiazide diuretics are created equal. Hydrochlorothiazide (Esidrix, HCTZ, Oretic) is the most widely prescribed by far. Although it is unquestionably effective, we prefer chlorthalidone. For one thing, it was the thiazide diuretic used in the ALLHAT that proved so beneficial in reducing strokes and other cardiovascular events. For another, chlorthalidone remains in the body longer than other thiazides and may be more effective in controlling blood pressure, especially during the
night.
Downside: Increased urination, since this is part of the way the drug works. Sexual dysfunction may be more likely than with some other blood pressure meds.
Side effects:
• Muscle cramps
• Difficulty breathing
• Confusion
• Mood changes
• Lethargy, fatigue
• Weakness
• Dry mouth, thirst
• Nausea, vomiting
• Irregular heart rhythm
• Symptoms are not a reliable indicator. Blood tests are essential.
Of course no one should ever discontinue any blood pressure medication without careful consultation with and supervision by a physician. Norvasc and similar drugs do have an important role in some heart conditions. But ALLHAT suggested that not all blood pressure medicines are created equal.
As much as we value thiazide diuretics in general, and chlorthalidone in particular, these are not perfect blood pressure–lowering drugs. Although they are inexpensive and effective, they can cause several serious side effects. One potential complication of diuretic treatment is elevation of blood sugar levels, which can lead to an increased risk of diabetes.
The biggest complication, however, is depletion of the essential minerals magnesium and potassium. It is important to have blood tests regularly to measure both of these electrolytes and make sure they are maintained within normal limits. Allowing the level of magnesium or potassium to stay low has serious negative health consequences. Both minerals must be kept in proper balance.
To get around the loss of potassium caused by many thiazide-type diuretics, physicians have switched to potassium-preserving diuretics such as amiloride (Midamor), spironolactone (Aldactone), and triamterene (Dyrenium).They are prescribed alone or more commonly in combination with hydrochlorothiazide (Aldactazide, Dyazide, Maxzide, and Moduretic). Such drugs have some of the same adverse reactions and precautions that standard diuretics have.
Potassium-preserving diuretics pose a significant problem when combined with ACE inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), quinapril (Accupril), and ramipril (Altace). Because the ACE inhibitors also help the body retain potassium, it is possible that one could end up with potassium overload. This is just as dangerous as too little potassium. Symptoms may include breathing difficulty, weakness, confusion, slow heart rate, and potentially life-threatening heart rhythm changes. Periodic blood tests are essential for a doctor to monitor the safe use of these medicines.
Aug
12
Dicyclomine - Digoxin - Diltiazem
August 12, 2009 | Leave a Comment
Generic Name
Dicyclomine (dih-SYE-kloe-meen) 10j
Brand Names
Bemote Dilomine
Bentyl Di-Spaz
Bycloft),e Or-Tyl Dibent
Type of Drug
Antispasmodic and anticholinergic.
Prescribed For
Irritable bowel, spastic colon, and similar digestive problems; also prescribed for colic in children over age 6 months.
General Information
Dicyclomine hydrochloride has been used for many years to calm “nervous stomach.” It and other anticholinergics work by blocking the effects of the neurohormone acetylcholine in the gastrointestinal (GI) tract. This reduces the mobility of the GI tract and slows the production of enzymes and other secretions.
Cautions and Warnings
Do not take dicyclomine if you are allergic or sensitive to any of its ingredients.
Dicyclomine should not be used by those with obstructive disease of the GI or urinary tract, severe ulcerative colitis, reflux esophagitis, acute bleeding with unstable heart function, myasthenia gravis, or glaucoma.
Dicyclomine should not be used in infants less than age 6 months or by breastfeeding mothers.
This drug should be used with caution if you have heart disease, Down’s syndrome, spastic paralysis, reduced mobility of the stomach and lower esophagus, fever, urinary difficulties, enlarged prostate, hiatal hernia, intestinal paralysis, kidney or liver disease, rapid heartbeat, hyperthyroidism (overactive thyroid gland), high blood pressure, or ulcerative colitis.
Dicyclomine reduces your ability to sweat and may lead to heat exhaustion and heatstroke, which can be life-threatening. Avoid extended heavy exercise and limit your exposure to high temperatures.
Anticholinergenic psychosis has been reported by those taking anticholinergenics, but it usually resolves within 24 hours after discontinuation of the drug.
Possible Side EfferkS
♦ Common: dry mouth, dizziness, blurred vision, nausea, and lightheadedness.
V Less common: drowsiness, weakness, nervousness, constipation, and decreased sweating.
Possible Side Effects (continued)
♦ Rare: drug allergy (symptoms include rash, itching, lives,
and breathing difficulties), confusion, eye pain, dizziness
when rising quickly from a sitting or lying position, a bloated
feeling, difficult or painful urination, headache, memory
loss, and vomiting. Contact your doctor if you experience
any side effect not listed above.
Drug Interactions
• Antacids containing calcium or magnesium, citrates, sodium bicarbonate, and carbonic anhydrase inhibitor drugs may increase dicyclomine’s therapeutic effect and side effects.
• Combining dicyclomine with other anticholinergic drugs including atropine, belladonna, clidinium, glycopyrrolate, hyoscyamine, isopropamide, propantheline, and scopolamine may intensify side effects.
• Dicyclomine may reduce stomach acidity and blood levels of oral ketoconazole (an antifungal).
• Dicyclomine may decrease the therapeutic effects of anti-glaucoma medications. Taking dicyclomine with corticosteroids used to treat glaucoma may be hazardous.
• Dicyclomine may counteract the effect of metoclopramide in reducing nausea and vomiting.
• Taking dicyclomine with a narcotic pain reliever may cause severe constipation.
• Taking this or any drug that slows the movement of stomach and intestinal muscles with a potassium chloride supplement –especially one in wax-matrix tablet form—may lead to excessive irritation of the stomach.
• Combining dicyclomine with amantadine, certain drugs to control heart rhythm, antihistamines, nitrates or nitrites, may increase dicyclomine side effects.
• Dicyclomine may increase the effects of atenolol and digoxin.
• Pftn0hiazine drugs, monoamine oxidase inhibitor antidepressants, benzodiazepines, and tricyclic antidepressants may increase side effects of dicyclomine. The effectiveness of phenothiazines to control psychotic symptoms may be decreased.
Food Interactions
Take dicyclomine on an empty stomach, a half hour before or 2 hours after a meal.
Usual Dose
Adult: 80-160 mg a day in 4 divided doses. Seniors should receive the lowest possible dosage and increase only as needed. Child (age 2 and over): 5-10 mg 3-4 times a day.
Child (age 6 months-2 years): 5-10 mg of syrup 3-4 times a day. Child (under 6 months): not recommended.
Overdosage
Symptoms include blurred vision; clumsiness; confusion; breathing difficulties; dizziness; drowsiness; dry mouth, nose, or throat; rapid heartbeat; fever; hallucinations; weakness; slurred speech; excitement, restlessness, or irritability; warmth; and dry or flushed skin. Take the victim to a hospital emergency room at once. ALWAYS bring the prescription bottle or container.
Special Information
Children taking dicyclomine may be more likely to develop high body temperature in hot weather and other side effects and should be carefully watched for side effects. Dicyclomine should not be given to infants or children unless the doctor decides that its use is absolutely necessary.
Call your doctor if you develop diarrhea, rash, flushing, eye pain, dry mouth, urinary difficulties, constipation, increased sensitivity to light, or any bothersome or persistent side effect.
Brush and floss your teeth regularly while taking this drug. Because dicyclomine may cause dry mouth, you may be more likely to develop cavities or other dental problems. Ice or hard candy may relieve dry mouth.
Constipation may be treated by using a laxative.
Dicyclomine may make you drowsy or tired and cause blurred vision. Be careful when driving or doing any task that requires concentration.
If you forget take it as soon as you remember. If it is almost time for your next dose, skip the dose you forgot and continue with your regular schedule. Do not take a double dose.
Special Populations
Pregnancy/Breast-feeding: A few cases of human malformation were linked to dicyclomine, but studies have shown that the drug has no effect on the fetus. When this drug is considered crucial by your doctor, its potential benefits must be carefully weighed against its risks.
Dicyclomine can reduce the amount of milk produced. Infants given dicyclomine may faint, go limp, and develop breathing problems and seizures. Nursing mothers who must take this drug should use infant formula.
Seniors: Seniors may be more susceptible to side effects, especially memory loss, changes in mental state, and glaucoma. Seniors may obtain maximum benefit with smaller dosages.
Generic Name
Digoxin (dih-JOX-in) A
Brand Names Digitek
Lanoxicaps
Lanoxin
Type of Drug Cardiac glycoside.
Prescribed For
Congestive heart failure (CHF) and other heart conditions involving a very rapid heartbeat.
General Information
Digoxin works directly on heart muscle. It improves the heart’s pumping ability or helps to control its beating rhythm. People with heart failure often develop swelling of the lower legs, feet, and ankles; digoxin improves these symptoms by improving blood cir-
Digoxin is generally used as part of the lifelong treatment of CHF.
Cautions and Warnings
Do not use digoxin if you are allergic or sensitive to it. Digoxin allergies are rare.
Digoxin should not be used in people with ventricular fibril-
lation.
Digoxin should be used with caution in people with sick sinus
syndrome or incomplete AV block, as it may cause a worsening of these conditions.
Digoxin has been used to treat obesity. The risk of fatal heart rhythms associated with such treatment makes it extremely dangerous as weight-loss medication. Many heart disease symptoms may be associated with digoxin. Report any unusual side effects to your doctor at once.
Kidney disease may increase blood levels of digoxin. Your dosage may need adjustment.
Long-term use of digoxin may cause the body to lose potassium, especially since it is generally used in combination with diuretics (agents that increase urination). For this reason, be sure to eat a balanced diet and high-potassium foods—bananas, citrus fruits, melons, and tomatoes.
Digoxin should be used with caution in people with electrolyte disorders.
Digoxin requirements vary with thyroid status. If you are taking digoxin and your thyroid status changes, your doctor will have to alter your digoxin dosage.
Possible Side Effects
Adult and Senior
♦ Common: dizziness, headache, nausea, and diarrhea.
✓ Less common: appetite loss, vomiting, weakness, apathy, drowsiness, blurred or yellow-tinted vision, seeing halos around bright lights, depression, psychoses, confusion or disorientation, restlessness, hallucinations, delirium, seizure, nerve pain, abnormal heart rhythms, and slow pulse.
✓ Rare: Enlargement of the breasts has been reported after long-term use of digoxin. Contact your doctor if you experience any side effect not listed above.
Child
T Children are more likely to develop abnormal heart rhythms before they see yellow or green halos or spots and before they develop nausea, vomiting, diarrhea, or stomach pain. Any abnormal heart rhythms that develop while a child is taking digoxin should be assumed to be a side effect.
Drug Interactions
• Drugs that may increase the effect of digoxin are alprazolam, amiloride aminoglycoside antibiotics, amiodarone, anticholinergic drugs, benzodiazepines, captopril, clarithromycin, diltiazem, diphenoxylate, dipyridamole, erythromycin, esmolol, felodipine, flecainide, hydroxychloroquine, ibuprofen, indomethacin, itraconazole, nifedipine, nitrendipine, omeprazole, propafenone, propantheline, quinidine, quinine, spironolactone, tetracycline, tolbutamide, triamterene, and verapamil.
• Drugs that may decrease blood levels of digoxin include aminoglutethimide, aminoglycosides, aminosalicylic acid, antacids, anti-cancer combinations, antidiabetes medication, antihistamines, barbiturates, cholestyramine, colestipol, cyclosporine, kaolin-pectin mixtures, metoclopramide, oral kanamycin, oral neomycin, oral sulfonylureas, phenylbutazone, phenytoin and related anti-seizure drugs, rifampin, St. John’s wort, sucralfate, and sulfasalazine.
• Disopyramide may alter the effects of digoxin, although the exact interaction is not well understood.
• Thiazide and loop diuretics, furosemide, ethacrynic acid, and bumetanide increase digoxin’s effect and increase the risk of side effects.
• Spironolactone may increase or decrease the side effects of digoxin; amiloride may reduce the effect of digoxin on the force of heart contraction.
• The effects of digoxin on the heart may be additive to those of ephedrine, epinephrine and other stimulants, beta blockers, calcium salts, procainamide, and rauwolfia drugs.
• Digoxin dosage must be adjusted when it is combined with a thyroid drug.
Food Interactions
These drugs may generally be taken without regard to meals. Taking your medication after a high-fiber meal reduces the amourxtcil drug absorbed into your blood.
Usual OQSS
Adult and Child (age 10 and over): starting dosage—known as the digitalizing or loading dose—is about 4-7 mcg per lb. of body weight. Digitalization may also be accomplished with a lower dosage over 7 days. Maintenance dosage 0.125-0.5 mg; it must be corrected for kidney function. For seniors, a lower dosage is required.
Child (under age 1o): starting dosage-5-30 mcg per lb. of body weight. Maintenance dosage-20-35% of the starting dosage. Careful measurement of your child’s digoxin dosage is crucial to safe and effective treatment.
Overdosage
Adult: Symptoms include appetite loss, nausea, vomiting, diarrhea, headache, weakness, apathy, blurred vision, yellow or green spots or halos before the eyes, yellowing of the skin or whites of the eyes, and changes in heartbeat.
Senior: Vomiting, diarrhea, and eye trouble are frequently seen. Child: An early sign is a change in heart rhythms.
Call your doctor immediately if any of these symptoms appear. Take the victim to a hospital emergency room. ALWAYS bring the prescription bottle or container.
Special Information
Take each day’s dose at the same time of day.
Do not stop taking digoxin without your doctor’s knowledge.
Lanoxicaps are better absorbed than tablet forms of digoxin. For this reason, each dose of Lanoxicaps is slightly lower than the corresponding digoxin tablet.
Avoid over-the-counter diet and cold medications containing stimulants.
Call your doctor at once if you develop side effects.
There may by some variation between digoxin tablets from different manufacturers. Do not change drug brands without telling your doctor.
Check your pulse every day—your doctor will teach you how—and call your doctor if it drops below 60 beats per minute.
If you forget a dose and remember at least 12 hours before your next dose, take it right away. If you do not remember until it is less than 12 hours before your next dose, skip the one you forgot and continue with your regular schedule. Do “lot take a double dose. Call your doctor if you M1 a dose for 2 or more days.
Special Populations
Pregnancy/Breast-feeding: Digoxin crosses into the fetal circulation. While digoxin is sometimes used during pregnancy to treat fetal heart disease, women who are or might be pregnant should not take digoxin without their doctor’s approval. When your doc-tor considers this drug crucial, its potential benefits must be care-
fully weighed against its risks.
Small amounts of digoxin pass into breast milk. Nursing mothers who take digoxin should use infant formula.
Seniors: Seniors are more sensitive to digoxin’s effects, especially appetite loss. Seniors with impaired renal function may need lower
dosages.
Generic Name
Diltiazem (dil-TYE-uh-zem) 92
Brand Names
Cardizem Dilt-CD
Cardizem CD Diltia XT
Cardizem LA Diltzac
Cartia XT Taztia XT
Dilator XR Tiazac
Type of Drug
Calcium channel blocker.
Prescribed For
Angina pectoris, chronic stable angina, Raynaud’s disease, prevention of second heart attacks, tardive dyskinesia (severe side effects associated with antipsychotic and other drugs), and hypertension (high blood pressure).
General Information
Diltiazem hydrochloride is one of many calcium channel blockers available in the U.S. These drugs block the passage of calcium, an essential factor in muscle contraction, into the heart and smooth muscles. Such blockage of calcium interferes with the contraction of these muscles, which in turn dilates (widens) the veins and ves sels that supply blood to them. This ditatk”q effect reduces blood pressure, the amount 0 Oxygen used by the heart muscle, and the ~1A 0 blood vessel spasm. Diltiazem is therefore useful in treating not only hypertension but also angina pectoris, a condition related to poor oxygen supply to the heart muscle and characterized by brief attacks of chest pain.
Diltiazem affects the movement of calcium only into muscle cells; it has no effect on calcium in the blood.
Cautions and Warnings
Do not take d,1taz&m1f you are allergic or sensitive to any of its
ingredients.
Diltiazem can slow your heart and interfere with normal electrical conduction. For people with a condition called sick sinus syndrome, this can result in temporary heart stoppage.
Diltiazem should not be taken if you are having a heart attack or if you have lung congestion. Diltiazem should be taken with caution by people with heart failure because it can worsen that condition.
Low blood pressure may occur, especially in people also taking a beta blocker.
Studies have shown that people taking calcium channel blockers—usually those taken several times a day, not those taken once daily—have a greater chance of having a heart attack than people taking beta blockers or another medicine for the same purposes. Discuss this with your doctor to be sure you are receiving the best possible treatment.
Diltiazem can cause severe liver damage and should be taken with caution if you have had hepatitis or any other liver condition.
Caution should also be exercised if you have a history of kidney problems, although no clear tendency toward causing kidney damage is seen with this drug.
Possible Side Effects
♦ Common: dizziness, lightheadedness, weakness, head-
ache, and fluid accumulation in the hands, legs, or feet.
✓ Less common: low blood pressure, fainting, increase or decrease in heart rate, abnormal heart rhythm, heart failure, nervousness, fatigue, nausea, rash, tingling in the hands or feet, hallucinations, temporary memory loss, difficulty sleeping, diarrhea, vomiting, constipation, upset stomach, itching, unusual sensitivity to sunlight, paxnlu) or stiff joints, liver inflammation, and increased urination, especially at night.
Drug Interactions
• Diltiazem taken with a beta-blocking drug for hypertension is usually well tolerated, but may lead to heart failure in people with already weakened hearts.
• Calcium channel blockers, including diltiazem, may add to
the effects of digoxin. This effect is not observed with any
consistency, however, and only affects people with a large
amount of digoxin already in their systems.
• Cimetidine and ranitidine increase the amount of diltiazem in the bloodstream and may account for a slight increase in the drug’s effect.
• Diltiazem may increase blood levels of cyclosporine, carbamazepine, encainide, and theophylline, and thus increase the chance of side effects from these drugs.
• Diltiazem may cause a decrease in blood lithium levels, possibly undermining lithium’s antimanic effect.
• Calcium channel blockers may cause bleeding when taken alone or combined with aspirin.
Food Interactions
Diltiazem is best taken on an empty stomach, at least 1 hour before or 2 hours after meals.
Usual Dose
Immediate-Release Products 30-60 mg 4 times a day.
Sustained-Release/Extended-Release Products Cardizem CD: 120-480 mg once a day. Cardizem LA: 120-540 mg once a day. Cartia XT: 120-300 mg once a day. Dilacor XR: 180-480 mg once a day. Dilt-CD: 120-360 mg once a day. Diltia XT: 180-480 mg once a day. Diltzac: 120-360 mg once a day. Taztia XT: 120-150 mg once a day. Tiazac: 120-360 mg once a day.
Overdosage
Symptoms of diltiazem overdose are very low blood pressure and reduced heart rate. Overdose victims must be made to vomit with 1J)8C2c syrup—available at any pharmacy—within 30 minutes of taking the overdose. Do not induce vomiting if the victim has fainted or is convulsing. If overdose symptoms have developed or more than 30 minutes have passed, vomiting is of little value. Take the victim to a hospital emergency room immediately. ALWAYS bring the prescription bottle or container.
Special information
Call your doctor if you develop any of the following symptoms! swelling of the hands, legs, or feet-, severe dizziness; constipation or nausea; or very low blood pressure.
Do not open, chew, or crush sustained-release capsules of
diltiazem.
If you take your diltiazem 3 or 4 times a day and forget a dose, take it as soon as you remember. Space the remaining doses throughout the rest of the day. If you take diltiazem 1 or 2 times a day and forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the one you forgot and continue with your regular schedule. Never take a double dose.
Special Populations
Pregnancy/Breast-feeding: In animal studies. high doses of diltiazem interfered with the development of the fetus. Diltiazem should not be taken by women who are or might be pregnant. When your doctor considers this drug crucial, its potential benefits must be carefully weighed against its risks.
Because diltiazem passes into breast milk, nursing mothers taking this drug should use infant formula.
Seniors: Seniors may be more sensitive to the effects of this drug because it takes longer to pass out of their bodies.
Jul
16
Acetaminophen
July 16, 2009 | Leave a Comment
Generic Name
Acetaminophen (uh-SEE-tuh-MIN-uh-fen) RE
Brand Names
Acephen Mapap-
Aceta Mapap Children’s
Acetaminophen Uniserts Mapap Extra Strength
Apacet Mapap Infant Drops
Aspirin Free Anacin Maximum Maranox
Strength Neopap
Aspirin Free Pain Relief Oraphen-PD
Dynafed, Children’s JR Panadol*
Dynafed EX Redutemp
Dynafed Extra Strength Silapap
Feverall Silapap Children’s
Feverall, Infants Silapap Infants
Genapap” Tapanol
Genebs Tempra*
Liquiprin Tylenol*
*Some products in this brand-name group are alcohol- or sugar-free. Consult your pharmacist.
Type of Drug
Antipyretic and analgesic.
Prescribed For
Relief of pain and fever for people who cannot or do not want to take aspirin or a nonsteroidal anti-inflammatory drug (NSAID). Acetaminophen may be given to children about to receive a
DTP vaccination to reduce the fever and pain that commonly follow the vaccination.
General Information
Acetaminophen is generally used to relieve pain and fever associated with the common cold, flu, viral infections, or other disorders where pain or fever may occur. It is also used to relieve pain in people who are allergic to aspirin, or those who cannot take aspirin because of potential interactions with other drugs such as oral anticoagulants. It can be used to relieve pain from a variety of sources, including arthritis, headache, muscle ache, menstrual cramping, and tooth and periodontic pain, although it does not reduce inflammation.
Cautions and Warnings
Do not take acetaminophen if you are allergic or sensitive to any of its ingredients. Do not take acetaminophen for more than 10 days in a row (5 days for children) unless directed by your doctor. Do not take more than is prescribed or recommended on the package.
Use this drug with extreme caution if you have kidney or liver disease or viral infections of the liver. Large amounts of alcohol increase the liver toxicity of large doses or overdoses of acetaminophen. Avoid alcohol if you regularly take acetaminophen. Some people are more sensitive to this effect than others.
Possible Side Effects
This drug is relatively free from side effects when taken in recommended doses. For this reason it has become extremely popular, especially among those who cannot take aspirin. V Rare: large doses or long-term use may cause liver dam-
age, rash, itching, fever, lowered blood sugar, stimulation,
yellowing of the skin or whites of the eyes, and/or a change
in the composition of your blood. Contact your doctor if
you experience any side effect not listed above.
Drug Interactions
o Large doses of barbiturate drugs, carbamazepine, phenytoin and similar drugs, izoniazid, rifampin, and sulfinpyrazone may increase the chances of liver toxicity if taken with acetaminophen.
• Alcoholic beverages increase the chances for liver toxicity
and possible liver failure associated with acetaminophen.
Food Interactions
None known.
Usual Dose
Adult and Child (age 12 and over): 325-650 mg 4-6 times a day,
or 1000 mg 3-4 times a day. Avoid taking more than 4 g (twelve
325-mg tablets) a day for long periods of time. Child (age 11): 480 mg 4-5 times a day. Child (age 9-10): 400 mg 4-5 times a day. Child (age 6-8): 320 mg 4-5 times a day. Child (age 4-5): 240 mg 4-5 times a day. Child (age 3): 160 mg 4-5 times a day. Child (age 1-2): 120 mg 4-5 times a day.
Child (age 4-11 months): 80 mg 4-5 times a day. Child (under age 4 months): 40 mg 4-5 times a day.
Overdosage
Acetaminophen is a commonly used ingredient in many over-the-counter (OTC) medications. Always check the list of ingredients when using more than one OTC medication to ensure that the combined dosage is within guidelines and to avoid accidental overdose.
Acute acetaminophen overdose may cause nausea, vomiting, sweating, appetite loss, drowsiness, confusion, abdominal tenderness, low blood pressure, abnormal heart rhythms, yellowing of the skin and whites of the eyes, and liver and kidney failure. Liver damage has occurred with 12 extra-strength tablets or 18 regular-strength tablets, but most people need larger doses-20 extra-strength or 30 regular-strength tablets—to damage their livers. Regular use of large doses for long periods-30004000 mg a day for a year—can also cause liver damage, especially if alcohol is involved. In case of overdose, induce vomiting as soon as possible with ipecac syrup—available at any pharmacy —and take the victim to a hospital emergency room. ALWAYS bring the acetaminophen bottle or container.
Special Information
Unless abused, acetaminophen is a beneficial, effective, and relatively nontoxic drug. Follow package directions and call your doctor if acetaminophen does not relieve pain in 10 days for adults or 5 days for children. Call your doctor if fever gets worse or persists longer than 3 days.
Alcoholic beverages will worsen the liver damage that acetaminophen can cause. People who take this drug on a regular basis should limit their alcohol intake.
If you forget to take a dose, take it as soon as you remember. If it is within an hour of your next dose, skip the dose you forgot and continue with your regular schedule. Do not take a double dose.
Special Populations
Pregnancy/Breast-feeding: Acetaminophen ‘is considered safe during pregnancy when taken in usual doses. Taking continuous high doses of the drug may cause birth defects or interfere with fetal development. Three cases of congenital hip dislocation appear to have been associated with acetaminophen. Check with your doctor before taking this drug if you are or might be pregnant.
Small amounts of acetaminophen may pass into breast milk, but the drug is considered harmless to nursing infants.
Seniors: Seniors may take acetaminophen as directed by a doctor.