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Jun

29

Patient Information Before Taking Effexor

June 29, 2011 | Leave a Comment

Effexor Precautions:

Before taking Effexor tell your doctor if you have an allergic reaction. Your doctor or pharmacist if you have about your health problems, to provide health care, especially if you have problems such as personal or family history of mental disorder (eg, bipolar / manic-depressive disorder), personal and family history of suicide attempts bleeding, loss of body water (dehydration), glaucoma, high blood pressure, heart problems (eg, irregular heartbeat, chest pain, heart failure, stroke), disorders, thyroid problems, high cholesterol, kidney disease, illness liver, low blood sodium (eg, hyponatremia). This drug may make you dizzy or drowsy. Use caution while driving, using machinery, or any other activity that requires alertness. Avoid drinking alcohol. Older people are more sensitive to side effects from medications. Older people are more likely to lose too much salt (hyponatremia) of the body, especially if they also take “water pills” (diuretics) with this medication. In children, the drug can affect the height and weight. Consult your doctor or pharmacist for more information. Effexor is not recommended for use during pregnancy. It may harm an unborn baby. In addition, children born to mothers who used the drug during the last 3 months of pregnancy may rarely develop symptoms such as feeding problems / labored breathing, seizures, muscle stiffness, and constant crying. If you notice any of these symptoms in your newborn, tell your doctor immediately. If you are planning pregnancy, become pregnant, and think about it, immediately discuss the benefits and risks of using this medication during pregnancy with your doctor. This medication passes into breast milk and may have undesirable effects on infants. Breast-feeding is not recommended while using effexor. Consult your doctor before breast-feeding.

Buy generic Effexor online at a cheap price without a prescription, but consult a doctor before and get full information on this popular depression treatment drug.

Jun

28

Flomax (Tamsulosin)

June 28, 2011 | Leave a Comment

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May

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Generic Drugs: Is There a Difference Between Generic Drugs and Brand?

May 30, 2011 | Leave a Comment

Before patients buy generic drugs online they want to know the answers to some of their questions, regarding generics. Why can one buy generic drugs cheap? Are generic drugs effective? Where can I buy generic drugs without a prescription cheap?

Today a lot of online pharmacies offer cheap generic drugs without a prescription and thousands of patients around the world take the opportunity to save on very expensive brand medications from a local pharmacy store. Generics are full analogues of brand ones, but are available to order online cheaper. Online pharmacies sell some drugs without a prescription which makes generic drugs purchase online even more convenient as you do not have to see a doctor.

Patients of all age groups and walks of life want to be treated effective and quality medicine. But here’s to suit all your medicines in different ways: some prefer to buy expensive original drugs, while others believe that lower-cost counterparts in no way inferior to well-known brands. In short, demand is there for any kind of drugs, as ill and eating a man does not stop never. What to and enjoy all kinds of pharmaceutical companies, letting the world market many drugs under various trade names.

According to recent statistics, the proportion of generic counterparts of drugs (generics) in the markets of many countries will only increase. Although the dynamics of growth is not the same: if the U.S. resorted to the use of generic drugs in approximately 15% of the treatment of diseases in Europe - 40-50%, in the post-Soviet countries - up to 80-90%. But do not be afraid of these numbers. Because generic - a quality product, which according to its pharmacological data of the original copies. The active substance in the analog and the original is absolutely identical. But the price of drugs is much different. And obviously for the benefit of generics. Why is this happening? To do this, to understand the differences in the production of both options medication.

When a pharmaceutical company synthesized a new drug, it is patent the name and performs a full spectrum of possible research - from clinical to experimental. Their progress is determined by: the exact formula, the effectiveness of the drug and all its side effects. At this preliminary stage can take up to 10 years. If we consider that a patent for the drug is given by an average of 20 years (sometimes 25), then for the remaining 10-15 years “exclusive use” producer has to invest heavily in the campaign, so with the help of massive purchases “recapture” the cost of wasted millions to test and make a profit. It is clear that the original price of such drugs will be essential.

What happens after the expiration of a patent? Right to manufacture the same drug, but under a different name may acquire any other company. Since emerging on the market, for example, not nootropil, and piracetam. This medicine is an exact copy of an analog, but since its production has already spent far less money, and it determines the selling price, which is an order of magnitude lower. So the generic - a kind of high-quality tracing paper once a patented drug, but at an affordable cost for a wide range of customers.

Dzhenericheskie drugs all over the world before they go on sale are thoroughly tested for compliance with the equivalence of the original drug. Such a study is conducted in three areas:

Pharmaceuticals - medicines should:
contain the same active ingredients;
introduced an identical manner;
be similar in concentration and its effect on the body.
Biological - the deviation between the analogs and copies are allowed no more than 15-20% of such parameters:
period of drug intake;
time to reach maximum concentration;
type and duration of excretion from the body.
Clinical - generic shall match the original for these indicators:
active substance;
security;
efficiency.

Thus, the generic is a quality drug, which contains the same active ingredient as the original drug, same adjuvants and production technology.

Summarizing the above, conclusions can be drawn: the use of generic drugs is absolutely justified, since it gives the doctor and patient choice; can treat almost all people from different walks of life, available in a price range, efficient and safe. In addition, taking a growing niche market of medicines, generic drugs stimulate the company’s original look promising new directions in drug development.

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May

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Tenormin (Atenolol)

May 21, 2011 | Leave a Comment

Tenormin (Atenolol)

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Generic Name: Atenolol
Brand Name: Tenormin
Generic Ingredients: Tenormin + Chlorthalidone Tenoretic
Generic Ingredient: Nebivolol Systolic
Type of Drug: Beta-adrenergic blocking agent.

Prescribed For: Tenormin alone or in combination is prescribed for high blood pressure, abnormal heart rhythms, angina pectoris, and prevention of second heart attack and migraine. It is also usedto treat alcohol withdrawal, stage Ifight, and other anxieties. Nebivolol is currently approved only to treat high blood pressure. Both are used together with other blood-pressure-lowering medications.

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General Information

Tenormin is one of many beta-adrenergic blocking drugs, or beta blockers and primarily blocks the beta, receptor. Nebivolol blocks both the beta, and beta, receptors when taken at high doses by people whose liver breaks down the drug more slowly than average. These drugs interfere with the action of adrenaline and other chemicals in the body that affect many body functions. Individual beta blockers have different characteristics that can make them more suitable for certain conditions or people.
When used to treat high blood pressure, Tenormin may be used either alone or concurrently with other antihypertensive drugs, particularly with a thiazide-type diuretic.

Cautions and Warnings

Do not take these drugs it you are allergic or sensitive to any of their ingredients or to other beta blockers. People with a severe allergy to any substance may be more sensitive to that allergen while taking a beta blocker.
People with angina who take these medicines for high blood pressure risk aggravating their angina if they suddenly stop taking the drug. These people should have their drug dosage reduced gradually over 1-2 weeks.
Tenormin should not be used by those with slow heartbeat, moderate to severe heart block (a condition affecting the heart’s conduction system), congestive heart failure unless it is due to a quickened heart rate that can be treated with Tenormin, or acute heart failure.
Tenormin and nebivolol should be used with caution if you have liver or kidney disease, because your ability to eliminate these drugs from your body may be impaired. Dose adjustments may be needed.
These drugs reduce the amount of blood the heart pumps. This reduction in blood flow may aggravate the condition of people with poor circulation or circulatory disease.
If you are undergoing major surgery, your doctor may want you to stop taking these drugs at least 2 days before surgery.
If you have pheochromocytoma (adrenal gland tumor), use Tenormin with caution.
Tenormin should be usedOfti caution in those with chronic bronchitis, emphysema, or other nonallergic bronchospastic diseases.
People with a history of severe anaphylactic reaction to allergens may be unresponsive to usual doses of epinephrine while taking beta blockers.

Possible Side Effects

Tenormin

Side effects are relatively uncommon and usually mild; they usually develop early in the course of treatment and are rarely a reason to stop taking Tenormin.
Most common: impotence.
Less common: unusual tiredness or weakness, slow heartbeat, heart failure (symptoms include swelling of the legs, ankles, or feet), dizziness, breathing difficulties, bronchospasm, depression, confusion, anxiety, nervousness, sleeplessness, disorientation, short-term memory loss, emotional instability, cold hands and feet, constipation, diarrhea, nausea, vomiting, upset stomach, increased sweating, urinary difficulties, cramps, blurred vision, rash, hair loss, stuffy nose, facial swelling, itching, chest pain, back or joint pain, colitis, drug allergy (symptoms include fever and sore throat), and liver toxicity.
Rare: lupus erythematosus (chronic condition affecting the body’s connective tissue). Contact your doctor if you experience any side effect not listed above.

Drug Interactions

•    Tenormin may interact with surgical anesthetics to increase the risk of heart problems during surgery. Some anesthesiologists recommend gradually stopping the drug by 2          days before surgery.
•    Tenormin may interfere with the normal signs of low blood sugar and with oral antidiabetic drugs.
•    Tenormin increases the blood-pressure-lowering effects of
other blood-pressure-reducing agents, including clonidine,
guanabenz, and reserpine; and calcium channel blockers,such as nifedipine.
•    Aspirin-containing drugs, indomethacin, and sulfinpyrazone may interfere with the blood-pressure-lowering effect of atenoloi.
•    Cocaine may reduce the effectiveness of all beta blockers.
•    Tenormin may worsen the problem of cold hands and feet associated with taking ergot alkaloids, used to treat migraine. Gangrene is a possibility in people taking both           anergot and Tenormin.
•    Tenormin will counteract thyroid hormone replacements.
•    Calcium channel blockers, diphenhydramine, flecainide, hydralazine, contraceptive drugs, propafenone, haloperidol, phenothiazine sedatives—molindone and others—quinolone         antibacterials, and quinidine may increase the amount of Tenormin in the bloodstream and lead to increased Tenormin effects.
•    Tenormin should not be taken within 2 weeks of taking a monoamine oxidase inhibitor (MAGI) antidepressant.
•    Cimetidine increases the amount of Tenormin absorbed into the bloodstream from oral tablets.
•    Tenormin may interfere with the effectiveness of some anti-asthma drugs, including theophylline and aminophylline, and especially ephedrine and isoproterenol.
•    Combining Tenormin with phenytoin or digitalis drugs may result in excessive slowing of the heart, possibly causing heart block (disruption of the electrical impulses that       control heart rate).
•    If you stop smoking while taking Tenormin, your dose may have to be reduced because your liver will break down the drug more slowly.
•    Aluminum salts, barbiturates, calcium salts, cholestyramine, colestipol, ampicillin, and rifampin may reduce the effectiveness of Tenormin.
•    Beta blockers may increase the effects of gabapentin, lidocaine, or prazosin, leading to undesirable reactions or toxicity.
•    Beta blockers may block the effects of epinephrine.
•    Fluoxetine, paroxetine, bupropion, propafenone, quinidine, duloxetine, and terbinafine can substantially increase the amount of nebivolol in the blood by interfering with        its breakdown by liver enzymes. Amiodarone, cimetidine, and sertraline also have this interaction but the effect is smaller. Avoid these combinations.
•    Other drugs that can increase nebivolol levels but to a much smaller extent are antihistamines, celecoxib, chlorpheniramine, chlorpromazine, citalopram, clemastine,           clomipramine, diphenhydramine, doxepin, doxorubicin, escitalopram, halotantrine, histamine, hydroxyzine, levomepromazine, methadone, metoclopramide, mibefradil, midodrine,       moclobemide, perphenazine, ranitidine, haloperidol, ritonavir, ticlopidine, and tripelennamine.
•    Dexamethasone, rifampin, and sildenafil reduce blood levels of nebivolol but the combined effect on blood pressure is moderate.

Food Interactions

These drugs may be taken without regard to food or meals.

Usual Dose:

Tenormin

Adult: 50 mg a day. Some people may require doses of 100-200 mg a day. Dosages over 100 mg a day are not likely to produce additional benefit to those being treated for hypertension. People with kidney disease may need only 50 mg every other day. Older adults should be treated more cautiously and may need a lower dose.
Child: not recommended.

Overdosage

Symptoms of overdose include changes in heartbeat—unusually slow, unusually fast, or irregular—severe dizziness or fainting, breathing difficulties, bluish-colored fingernails or palms, and seizures. Heart failure and shock may also result from a beta blocker overdose. The victim should be taken to a hospital emergency room. ALWAYS bring the prescription bottle or container.

Special Information

These drugs are meant to be taken continuously.
When ending treatment, dosage should be reduced gradually over a period of about 2 weeks. Do not stop taking these drugs unless directed to do so by your doctor. Abrupt withdrawal may cause chest pain, breathing difficulties, increased sweating, and unusually fast or irregular heartbeat.
Call your doctor at once if you develop back or joint pain, breathing difficulties, cold hands or feet, depression, rash, or changes in heartbeat. Tenormin may produce an undesirable lowering of blood pressure, leading to dizziness or fainting; call your doctor if this happens. Call your doctor if you experience persistent or bothersome anxiety, diarrhea, constipation, impotence, headache, itching, nausea or vomiting, nightmares or vivid dreams, upset stomach, insomnia, stuffy nose, frequent urination, unusual tiredness, or weakness.
Tenormin may cause drowsiness, lightheadedness, dizziness, or blurred vision. Be careful when driving or performing complex tasks.
It is best to take beta blockers at the same time each day. If you forget a dose, take it as soon as you remember. If you take nebivolol and do not remember until your next dose, continue with your regular schedule. If you take Tenormin once a day and it is within 8 hours of your next dose, skip the dose you forgot and continue with your regular schedule. If you take Tenormin twice a day and it is within 4 hours of your next dose, skip the one you forgot and continue with your regular schedule. Never take a double dose of Tenormin or nebivolol.

Special Populations

Pregnancy/breast-feeding: Infants born to women who took a beta blocker while pregnant had lower birth weights, low blood pressure, and reduced heart rates. These drugs should be avoided by pregnant women and women who might become pregnant while taking them.
Tenormin and nebivolol pass into breast milk. Nursing mothers should use infant formula.
Seniors: Seniors taking Tenormin should use the lowest effective dose as this group is more likely to have decreased heart, kidney, and liver function, and to be taking additional medications. Dosage adjustment of nebivolol is not necessary in seniors.

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Aug

12

Dicyclomine - Digoxin - Diltiazem

August 12, 2009 | Leave a Comment

Acyclovir

July 16, 2009 | Leave a Comment

Generic Name
Acyclovir
Brand Name Zovirax
Type of Drug Antiviral.
Prescribed For
Initial treatment and maintenance of genital herpes outbreaks; treatment of herpes zoster (shingles); and treatment of varicella (chickenpox).
General Information
Acyclovir is the only oral drug that reduces growth rates of the herpes virus and the related viruses, Epstein-Barr, varicella, and cytomegalovirus (CMV); both oral acyclovir and oral ganciclovir work against CMV Intravenous drugs, including acyclovir injection, may also be used for these viral infections; however, intravenous antiviral drugs are usually reserved for patients with HIV, cancer, or otherwise compromised immune systems.
Acyclovir is selectively absorbed into cells that are infected with the herpes simplex virus, where it is converted into its active form. Acyclovir works by interfering with the reproduction of viral DNA, slowing the growth of existing viruses. It has little effect on recurrent infections. To treat both local and systemic (whole-body) symptoms acyclovir must be given by intravenous injection or taken by mouth. Local symptoms may be treated with the ointment alone. Oral acyclovir may be taken every day to reduce the number and severity of herpes attacks in people who suffer 10 or more attacks a year; it may also be used to treat intermittent attacks as they occur, but treatment must be started as soon as possible to have the greatest effect.
Cautions and Warnings
Do not use acyclovir if you are allergic or sensitive to any of its ingredients. Do not use acyclovir ointment if you have had an allergic reaction to it or to the major component of the ointment base, polyethylene glycol. Do not apply acyclovir ointment inside the vagina because the polyethylene glycol base may cause irritation and swelling of sensitive vaginal tissue. Acyclovir ointment is not intended for use in the eye and should not be used to treat a herpes infection of the eye.
Renal failure has occurred in patients using oral acyclovir, in some cases resulting in death. People with kidney impairment should have dosages adjusted accordingly.
Maintain adequate hydration while taking oral acyclovir. Animal testing indicates that acyclovir may affect fertility in men. These effects may be reversible.
Possible Side Effects
Capsules, Suspension, and Tablets
✓    Most common: feeling unwell, headache, diarrhea, nausea, and vomiting.
✓    Less common: appetite loss, stomach gas, constipation, fatigue, rash, leg pains, sore throat, a bad taste in the mouth, sleeplessness, and fever.
♦    Rare: aching joints, weakness, and tingling in the hands or feet. Contact your doctor if you experience any side effect not listed above.
Ointment
✓    Most common: mild burning, irritation, rash, and itching. These effects are more likely to occur when treating an initial herpes attack than a recurrent attack. Women are 4 times more likely to experience burning than men.
Drug Interactions
•    Do not apply acyclovir together with any other ointment or topical medication.
•    Oral probenecid may decrease elimination of acyclovir from the body, which increases blood levels of oral or injected acyclovir, increasing the risk of side effects.
•    Combining acyclovir and zidovudine (an HIV drug—also known as AZT) may lead to severe drowsiness and lethargy.
Food Interactions
Acyclovir may be taken with food if it upsets your stomach.

Usual Dose
Capsules, Suspension, and Tablets
Adult: genital herpes attack-200 mg every 4 hours, 5 times a day for 10 days. Recurrent infections-400 mg 3 times a day or 200 mg 5 times a day for 5 days. Suppressive therapy for chronic herpes-800 mg a day, every day for up to a year. Herpes zoster800 mg 5 times a day for 7-10 days.
Child (age 2 and over): Acyclovir has been given to children in daily doses as high as 36 mg per lb. of body weight without any unusual side effects.
Child (under age 2): not recommended.
If you have kidney disease, your doctor should adjust your dose according to the degree of functional loss.
Ointment: Apply every 3 hours, 6 times a day for 7 days. Apply enough medication to cover all visible skin lesions. About 1/2 in. of ointment should cover about 4 sq. in. of lesions. Your doctor may prescribe a longer course of treatment to prevent the delayed formation of new lesions over the duration of an attack. Begin using ointment at the first sign of an attack.
Overdosage
Overdose of oral acyclovir may lead to kidney damage due to deposits of acyclovir crystals in the kidneys. Other side effects include agitation, seizures, lethargy, and coma. The risk of experiencing toxic side effects from swallowing acyclovir ointment is quite small. In the case of overdose or accidental ingestion, call your poison control center. ALWAYS bring the prescription bottle or container.
Special Information
Use a finger cot or rubber glove when applying acyclovir ointment to protect against inadvertently spreading the virus. Be sure to apply the medication exactly as directed and to completely cover all lesions. Keep affected areas clean and dry. Loose-fitting clothing will reduce possible irritation of a healing lesion. If you skip several doses, or a day or more of treatment, the drug will not exert its maximum effect.
Acyclovir is not a cure for genital herpes. Herpes may be transmitted even if you do not have symptoms of active disease. To avoid giving the condition to a sexual partner, do not have intercourse while visible herpes lesions are present. A condom offers some protection against transmission of the herpes virus, but spermicidal products and diaphragms do not. Acyclovir alone will not prevent herpes transmission.
Initiate therapy at the first sign of symptoms.
Women with genital herpes have an increased risk of cervical cancer. Speak with your doctor about the need for an annual Pap smear.
Call your doctor if acyclovir does not relieve your symptoms, if side effects become severe or intolerable, or if you become pregnant or want to begin breast-feeding. Check with your dentist if you notice swelling or tenderness of the gums.
Avoid exposure to excessive sunlight or sunlamps because of unusual sensitivity caused by oral acyclovir.
Special Populations
Pregnancy/Breast-feeding: Acyclovir crosses into the circulation of the fetus. Animal studies have shown that large doses—up to 125 times the human dose—cause damage to both mother and fetus. While there is no information to indicate that acyclovir affects a human fetus, do not use it during pregnancy unless it is specifically prescribed by your doctor and the possible benefit outweighs the risk.
Acyclovir passes into breast milk in concentrations up to 4 times the concentration in blood, and it has been found in the urine of a nursing infant. Although no side effects have been found in nursing babies, mothers who must take acyclovir should use infant formula.
Seniors: Shingles attacks in people over age 50 tend to be more severe and respond best to acyclovir treatment if the drug is started within 48-72 hours of the appearance of the first rash. Seniors with reduced kidney function should be given a lower dose of oral acyclovir than younger adults.

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Jun

29

Patient Information Before Taking Effexor

Jun

28

Flomax (Tamsulosin)

May

30

Generic Drugs: Is There a Difference Between Generic Drugs and Brand?

May

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Tenormin (Atenolol)

Aug

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Dicyclomine - Digoxin - Diltiazem

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Cholinesterase Inhibitors

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Cholestyramine

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Acyclovir